vexibinol

Known as: 5,7,2',4'-tetrahydroxy-8-lavandulyl-flavanone, sophoraflavanone G 
 
National Institutes of Health

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Flavanones

Papers overview

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2016
2016
Anti-neuroinflammatory effect of Sophoraflavanone G from Sophora alopecuroides in LPS-activated BV2 microglia by MAPK, JAK/STAT and Nrf2/HO-1 signaling pathways.
BACKGROUND Neuroinflammation plays a vital role in Alzheimer's disease (AD) and other neurodegenerative conditions. Sophora… Expand
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2016
2016
Sophoraflavanone G prevents Streptococcus mutans surface antigen I/II-induced production of NO and PGE2 by inhibiting MAPK-mediated pathways in RAW 264.7 macrophages.
BACKGROUND Sophora flavescens AITON (Leguminosae) is a typical traditional Korean medical herb considered to exhibit… Expand
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2016
2016
Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264.7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO-1 pathways.
Sophoraflavanone G (SG), a prenylated flavonoid from Sophora alopecuroides, has been reported to have many pharmacological… Expand
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2016
2016
Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation.
Sophoraflavanone G (SG) was isolated from Sophora flavescens. Previously, we have found that SG is able to suppress the… Expand
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2016
2016
Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis
Rhizoma Drynariae (RD), as one of the most common clinically used folk medicines, has been reported to exert potent anti… Expand
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2013
2013
Identifying 2 prenylflavanones as potential hepatotoxic compounds in the ethanol extract of Sophora flavescens.
Zhixue capsule is a prescription for hemorrhoid commonly used in traditional Chinese medicine. This drug was recalled by the… Expand
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2013
2013
Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs.
Aberrantly activated signal transducer and activator of transcription (STAT) proteins are implicated with human cancers and… Expand
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2010
2010
PHYTONCIDES AND PHYTOALEXINS - VEGETAL ANTIBIOTICS
Phytoncides and phytoalexins are antibiotic substances that have been isolated from a large number of plants .Tropical plants in… Expand
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2007
2007
Antibacterial activity of sophoraflavanone G isolated from the roots of Sophora flavescens.
This study investigated the antibacterial activities of sophoraflavanone G from Sophora flavescens in combination with two… Expand
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1998
1998
Anti-MRSA activity of sophoraflavanone G and synergism with other antibacterial agents.
Anti-MRSA activity of sophoraflavanone G (SFG) and synergism between SFG and antibacterial agents against MRSA (methicillin… Expand
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