velaglucerase alfa

Known as: EC 3.2.1.45, Human Glucosylceramidase (EC 3.2.1.45 or Beta-Glucocerebrosidase), Glycoform Alpha 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
0246820102018

Papers overview

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2014
2014
AIM Pregnancy and delivery are affected by and - in turn - impact signs and symptoms of Gaucher disease (GD). Prior to enzyme… (More)
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2013
2013
Type 1 Gaucher disease (GD1), resulting from glucocerebrosidase deficiency, leads to splenomegaly, hepatomegaly, anemia… (More)
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2013
2013
Enzyme replacement therapy for Gaucher disease (GD) has been available since 1991. This study compared the efficacy and safety of… (More)
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2013
2013
Velaglucerase alfa is a glucocerebrosidase produced by gene activation technology in a human fibroblast cell line (HT-1080), and… (More)
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2011
2011
INTRODUCTION Therapeutic goals have been described to monitor achievement, maintenance and continuity of therapeutic response in… (More)
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2011
2011
Since bone pathology is a major concern in type 1 Gaucher disease (GD1), we evaluated bone mineral density (BMD) in adults… (More)
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2011
2011
Gaucher disease is an autosomal recessively inherited lysosomal storage disease that results from the defective activity of the… (More)
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2010
2010
Enzyme replacement therapy is the standard of care for symptomatic Gaucher disease. Velaglucerase alfa is a human beta… (More)
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2010
2010
In February 2010, velaglucerase alfa (Vpriv; Shire) was approved by the US Food and Drug Administration as a long-term enzyme… (More)
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2010
2010
Gaucher disease type 1 is caused by the defective activity of the lysosomal enzyme, acid beta-glucosidase (GCase). Regular… (More)
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