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varespladib

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long… Expand
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2018
2018
Phospholipase A2s (PLA2) is a major component of snake venom with diverse pathologic toxicities and, therefore, a potential… Expand
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Highly Cited
2016
Highly Cited
2016
Snakebite remains a neglected medical problem of the developing world with up to 125,000 deaths each year despite more than a… Expand
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2015
2015
Background Matrix metalloproteinase (MMP)‐2 deficiency makes humans and mice susceptible to inflammation. Here, we reveal an MMP… Expand
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2015
2015
The hydrolysis of the ester bond of glycerophospholipids is catalyzed by the family of enzymes Phospholipase A2 (PLA2), that… Expand
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Highly Cited
2014
Highly Cited
2014
IMPORTANCE Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2… Expand
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2012
2012
Secretory phospholipase A2 (sPLA2), which links surfactant catabolism and lung inflammation, is associated with lung stiffness… Expand
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2010
2010
Background— Secretory phospholipase A2 (sPLA2) may play a role in myonecrosis after elective percutaneous coronary intervention… Expand
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Highly Cited
2009
Highly Cited
2009
Secretory phospholipase A2 (sPLA2) activity promotes foam cell formation, increases proinflammatory bioactive lipid levels… Expand
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2009
2009
Phase II results of the trials of two phospholipase A2 inhibitors which may be of value in the treatment of atherosclerosis and… Expand
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