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- Publications
- Influence
Antitumor promoting and actioxidant activities of anthraquinones isolated from the cell suspension culture of Morinda elliptica
- Jasril, Md. Nordin Lajis, Y. Lim, M. A. Abdullah, Mohd Aspollah Sukari, A. Ali
- Chemistry
- 2003
Six anthraquinones (nordamnacanthal, alizarin-1-methyl ether, rubiadin, soranjidiol, lucidin-ω-methyl ether and morindone) isolated from the cell suspension culture of Morinda elliptica were assayed… Expand
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In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts
- Soek Sin Teh, G. Ee, +4 authors Z. Ahmad
- Biology, Medicine
- BioMed research international
- 8 September 2013
The in vitro cytotoxicity tests on the extracts of Mesua beccariana, M. ferrea, and M. congestiflora against Raji, SNU-1, HeLa, LS-174T, NCI-H23, SK-MEL-28, Hep-G2, IMR-32, and K562 were achieved… Expand
Cytotoxicity and Structure-Activity Relationships of Xanthone Derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora towards Nine Human Cancer Cell Lines
- Soek Sin Teh, G. Ee, Siau Hui Mah, Y. Lim, Z. Ahmad
- Chemistry, Medicine
- Molecules
- 1 February 2013
The cytotoxic structure-activity relationships among a series of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora were studied. Eleven xanthone derivatives identified… Expand
Phylattrin, a New Cytotoxic Xanthone from Calophyllum soulattri
- Siau Hui Mah, G. Ee, Soek Sin Teh, M. Rahmani, Y. Lim, R. Go
- Chemistry, Medicine
- Molecules
- 1 July 2012
Our continuing studies on secondary metabolites from the stem bark of Calophyllum soulattri has led to the isolation of another new diprenylated xanthone, phylattrin (1), in addition to five other… Expand
Artomandin, a new xanthone from Artocarpus kemando (Moraceae)
- G. Ee, Siow Hwa Teo, M. Rahmani, C. K. Lim, Y. Lim, R. Go
- Chemistry, Medicine
- Natural product research
- 31 May 2011
A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C (2), artonol B (3), and artochamin A (4), as well as β-sitosterol (5) were… Expand
Mesua beccariana (Clusiaceae), A Source of Potential Anti-cancer Lead Compounds in Drug Discovery
- Soek Sin Teh, Gwendoline Cheng Lian Ee, Siau Hui Mah, Y. Lim, M. Rahmani
- Biology, Medicine
- Molecules
- 1 September 2012
An investigation on biologically active secondary metabolites from the stem bark of Mesua beccariana was carried out. A new cyclodione, mesuadione (1), along with several known constituents which are… Expand
A new benzophenone from Mesua congestiflora, an inhibitor against human B lymphocyte cancer cell line
- G. Ee, Soek Sin Teh, H. C. Kwong, Siau Hui Mah, Y. Lim, M. Rahmani
- Chemistry
- 1 September 2012
Abstract An investigation on the secondary metabolites from the roots of Mesua congestiflora was carried out. A new benzophenone–congestiflorone ( 1 ) and one xanthone, α-mangostin ( 2 ) were… Expand
2-Methoxy-1,4-naphthoquinone (MNQ) induces apoptosis of A549 lung adenocarcinoma cells via oxidation-triggered JNK and p38 MAPK signaling pathways.
- Jeremy Yee Hoong Ong, P. V. C. Yong, Y. Lim, A. S. Ho
- Biology, Medicine
- Life sciences
- 15 August 2015
AIM
The compound 2-methoxy-1,4-naphthoquinone (MNQ) was previously shown to be cytotoxic against several cancer cell lines, but its mode of action is poorly understood. In this study, we aimed to… Expand
2-Methoxy-1,4-Naphthoquinone (MNQ) suppresses the invasion and migration of a human metastatic breast cancer cell line (MDA-MB-231).
- Kitson Liew, P. V. C. Yong, Y. Lim, V. Navaratnam, A. S. Ho
- Medicine
- Toxicology in vitro : an international journal…
- 1 April 2014
Metastasis contributes to the escalating mortality rate among cancer patients worldwide. The search for novel and more effective anti-metastatic agent is crucial owing to the lack of anticancer drugs… Expand
Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation
- Wei Hsum Yap, Y. Lim
- Medicine
- Biochemistry research international
- 27 September 2015
Chronic inflammation drives the development of various pathological diseases such as rheumatoid arthritis, atherosclerosis, multiple sclerosis, and cancer. The arachidonic acid pathway represents one… Expand