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validamine

Known as: 1-amino-1,5,6-trideoxy-5-(hydroxymethyl)-D-chiro-inositol 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Inositol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
C-5a-substituted validamine type glycosidase inhibitors.
2013
2013
Enhanced Production of Acarbose and Concurrently Reduced Formation of Impurity C by Addition of Validamine in Fermentation of Actinoplanes utahensis ZJB-08196
Commercial production of acarbose is exclusively via done microbial fermentation with strains from the genera of Actinoplanes… 
2011
2011
Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesis.
Glycosyltransferases are ubiquitous in nature. They catalyze a glycosidic bond formation between sugar donors and sugar or… 
Review
2009
Review
2009
Design and synthesis of 5a-carbaglycopyranosylamime glycosidase inhibitors.
5a-Carba-alpha-D-glucopyranosylamine, validamine, and analogous compounds valienamine and valiolamine, have proved to be… 
2007
2007
Quantitative determination of valienamine and validamine by thin-layer chromatography.
A simple and valid thin-layer chromatographic method for the separation and quantitative determination of valienamine and… 
2002
2002
Synthesis of an alpha-fucosidase inhibitor, 5a-carba-beta-L-fucopyranosylamine, and fucose-type alpha- and beta-DL-valienamine unsaturated derivatives.
Discovery of a very potent alpha-fucosidase inhibitor 5a-carba-alpha-L-fucopyranosylamine led to preparation of its beta-anomer… 
2001
2001
Synthesis of 5-epi-[6-(2)H(2)]valiolone and stereospecifically monodeuterated 5-epi-valiolones: exploring the steric course of 5-epi-valiolone dehydratase in validamycin A biosynthesis.
In validamycin A biosynthesis, as well as that of acarbose, the valienamine and validamine moieties are ultimately derived from a… 
1997
1997
Preparation and biological activity of manno- and galacto-validamines, new 5a-carba-glycosylamines as alpha-glycosidase inhibitors.
Manno- and galacto-validamines, which are epimers of validamine, were semi-synthesized by the configurational inversion of… 
1992
1992
Enzymatic synthesis of glucoside derivatives of validamine and valienamine.
alpha- And beta-glucoside derivatives of validamine and valienamine were prepared by enzymatic transglucosidation using alpha… 
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