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valerenic acid

National Institutes of Health

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IndenesSesquiterpenes

Papers overview

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2016
2016
Effects of valerian on subjective sedation, field sobriety testing and driving simulator performance.
2016
2016
Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives
Valerenic acid (VA)—a β2/3-selective GABA type A (GABAA) receptor modulator—displays anxiolytic and anticonvulsive effects in… 
2012
2012
Application of Artificial Neural Network in Simulation of Supercritical Extraction of Valerenic Acid from Valeriana officinalis L.
Application of artificial neural network (ANN) has been studied for simulation of the extraction process by supercritical CO2… 
2011
2011
Efficient and scalable one-pot synthesis of 2,4-dienols from cycloalkenones: optimized total synthesis of valerenic acid.
A mild and selective one-pot procedure to provide 2,4-dienols from simple cycloalkenones in high yields is described. This… 
2011
2011
Three phases hollow fiber LPME combined with HPLC-UV for extraction, preconcentration and determination of valerenic acid in Valeriana officinalis.
2010
2010
Pharmacokinetics of valerenic acid after single and multiple doses of valerian in older women
Insomnia is a commonly reported clinical problem with as many as 50% of older adults reporting difficulty in falling and/or… 
2009
2009
Total synthesis of valerenic acid, a potent GABAA receptor modulator.
The first total synthesis of the sesquiterpenoid valerenic acid, a constituent of Valeriana officinalis, is described. The… 
2009
2009
Hepatic metabolism and biliary excretion of valerenic acid in isolated perfused rat livers: role of Mrp2 (Abcc2).
The study was designed to investigate the hepatic metabolism and transport system of valerenic acid, a main active constituent of… 
2005
2005
Pharmacokinetics of valerenic acid after administration of valerian in healthy subjects
Objectives: To describe the pharmacokinetics of valerenic acid in a group of healthy adults after a single oral dose of valerian… 
2001
2001
Valepotriates and valerenic acids in commercial preparations of valerian available in Australia.
Thirty-one commercial valerian preparations available in Australia, including teas, tablets, capsules and liquids, were analysed… 
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