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uropod

Known as: uropodium 
A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on… Expand
National Institutes of Health

Papers overview

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2013
2013
SHARPIN-deficient mice display a multiorgan chronic inflammatory phenotype suggestive of altered leukocyte migration. We… Expand
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Highly Cited
2012
Highly Cited
2012
Uropod elongation occurs during leukocyte extravasation. 
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Highly Cited
2011
Highly Cited
2011
Melanoma cells can switch between an elongated mesenchymal-type and a rounded amoeboid-type migration mode. The rounded ‘amoeboid… Expand
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Review
2009
Review
2009
Renewed interest in cell shape has been prompted by a recent flood of evidence that indicates that cell polarity is essential for… Expand
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Highly Cited
2008
Highly Cited
2008
Currently, no approved monoclonal antibody (mAb) therapies exist for human multiple myeloma (MM). Here we characterized cell… Expand
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Highly Cited
2007
Highly Cited
2007
We find that in contrast to strongly adherent, slow moving cells such as fibroblasts, neutrophils exert contractile stresses… Expand
Highly Cited
2001
Highly Cited
2001
Redistribution of specialized molecules in migrating cells develops asymmetry between two opposite cell poles, the leading edge… Expand
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Highly Cited
2000
Highly Cited
2000
Buffering of intracellular Ca2+ transients in human neutrophils leads to reduced motility due to defective uropod detachment on… Expand
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Highly Cited
1998
Highly Cited
1998
Chemokines as well as the signaling through the adhesion molecules intercellular adhesion molecule (ICAM)-3 and CD43 are able to… Expand
Highly Cited
1997
Highly Cited
1997
During activation, T lymphocytes become motile cells, switching from a spherical to a polarized shape. Chemokines and other… Expand
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