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uropod

Known as: uropodium 
A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on… Expand
National Institutes of Health

Papers overview

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2013
2013
SHARPIN-deficient mice display a multiorgan chronic inflammatory phenotype suggestive of altered leukocyte migration. We… Expand
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Highly Cited
2011
Highly Cited
2011
Melanoma cells can switch between an elongated mesenchymal-type and a rounded amoeboid-type migration mode. The rounded ‘amoeboid… Expand
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Review
2009
Review
2009
Renewed interest in cell shape has been prompted by a recent flood of evidence that indicates that cell polarity is essential for… Expand
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Highly Cited
2008
Highly Cited
2008
Currently, no approved monoclonal antibody (mAb) therapies exist for human multiple myeloma (MM). Here we characterized cell… Expand
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Highly Cited
2007
Highly Cited
2007
We find that in contrast to strongly adherent, slow moving cells such as fibroblasts, neutrophils exert contractile stresses… Expand
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Highly Cited
2001
Highly Cited
2001
Redistribution of specialized molecules in migrating cells develops asymmetry between two opposite cell poles, the leading edge… Expand
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Highly Cited
2000
Highly Cited
2000
Buffering of intracellular Ca2+ transients in human neutrophils leads to reduced motility due to defective uropod detachment on… Expand
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Highly Cited
2000
Highly Cited
2000
Syndecan-1 (CD138) is a heparan sulfate-bearing proteoglycan present on the surface of myeloma cells where it mediates myeloma… Expand
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Highly Cited
1998
Highly Cited
1998
Chemokines as well as the signaling through the adhesion molecules intercellular adhesion molecule (ICAM)-3 and CD43 are able to… Expand
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Highly Cited
1997
Highly Cited
1997
During activation, T lymphocytes become motile cells, switching from a spherical to a polarized shape. Chemokines and other… Expand
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