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uracil glycol

Known as: 5,6-dihydroxy-5,6-dihydrouracil, Ug cpd 
 
National Institutes of Health

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2012
2012
Spontaneous and oxidant-induced damage to cytosine is probably the main cause of CG to TA transition mutations in mammalian… Expand
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Review
2002
Review
2002
  • S. Wallace
  • Free radical biology & medicine
  • 2002
  • Corpus ID: 11852794
The principal oxidized cytosine bases, uracil glycol, 5-hydroxycytosine, and 5-hydroxyuracil, are readily bypassed, miscode, and… Expand
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Highly Cited
1999
Highly Cited
1999
Saccharomyces cerevisiae possesses two functional homologues (Ntg1p and Ntg2p) of the Escherichia coli endonuclease III protein… Expand
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Highly Cited
1998
Highly Cited
1998
A major stable oxidation product of DNA cytosine is uracil glycol (Ug). Because of the potential of Ug to be a strong… Expand
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Highly Cited
1998
Highly Cited
1998
The most common base substitution arising from oxidative damage of DNA is a GC --> AT transition. In an effort to determine the… Expand
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1997
1997
Endonuclease III of Escherichia coli excises a broad range of oxidized, hydrated and ring-fragmented pyrimidines from DNA. The… Expand
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Highly Cited
1995
Highly Cited
1995
Exposure of pyrimidines of DNA to ionizing radiation under aerobic conditions or oxidizing agents results in attack on the 5,6… Expand
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1994
1994
A variety of chemically modified oligonucleotides have been studied by matrix-assisted laser desorption/ionization time-of-flight… Expand
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Highly Cited
1993
Highly Cited
1993
The excision of modified bases from DNA by Escherichia coli endonuclease III was investigated. Modified bases were produced in… Expand
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Highly Cited
1986
Highly Cited
1986
OsO4 selectively forms thymine glycol lesions in DNA. In the past, OsO4-treated DNA has been used as a substrate in studies of… Expand
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