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ubiquitinyl hydrolase activity

Known as: ubiquitin C-terminal hydrolase, ubiquitin hydrolase activity, thiol-dependent ubiquitinyl hydrolase activity 
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin… 
National Institutes of Health

Related topics

Related topics

3 relations
thiol-dependent ubiquitin-specific protease activity

Narrower (2)

ubiquitin-specific protease activity involved in negative regulation of ERAD pathwayubiquitin-specific protease activity involved in positive regulation of ERAD pathway

Papers overview

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2019
2019
In vitro studies on the recognition of NF-κB p65 subunit by the deubiquitinase enzyme USP7
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) transcription factor family plays a key role in the… 
2019
2019
Inhibition of A20 deubiquitinase activity by KSHV vFLIP: A SUMO dependent mechanism?
KSHV vFLIP is a potent activator of NFκB signaling and an inhibitor of apoptosis and autophagy. Inhibition of vFLIP function and… 
2018
2018
Abstract 1859: Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells
Proteasome inhibitors kill cancer cells by inducing an acute proteotoxic stress response characterized by the cytosolic… 
2016
2016
Ubiquitin-interacting motifs confer K48 ubiquitin chain preference to the deubiquitinase activity of USP25
2015
2015
Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma
BRCA1‐associated protein 1 (BAP1) is a deubiquitinating enzyme that is involved in the regulation of cell growth. Recently, many… 
2014
2014
How does ubiquitin regulate synapses? Let me count the ways
Ubiquitination is a ‘ubiquitous’ cellular signalling system that can regulate the abundance and/or activity of proteins… 
2014
2014
Understanding two inhibitors of NF-κB: A20 and IκBβ
  • A. De
  • 2014
  • Corpus ID: 89032460
Inhibitors of NF-κB: A20 and IκBβ Arnab De While prompt activation of NF-κB is essential for optimal immune response, it is… 
2013
2013
High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity.
2010
2010
The A 20 Deubiquitinase Activity Negatively Regulates LMP 1 Activation of IRF 7
A20 possesses both deubiquitinase (DUB) and ubiquitin E3 ligase activities that are required for termination of Toll-like… 
2010
2010
Tumour suppressor CYLD is a negative regulator of the mitotic kinase Aurora‐B
The familial cylindromatosis tumour suppressor CYLD contains three cytoskeleton‐associated protein glycine‐rich (CAP‐Gly) domains… 
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