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thiol-dependent ubiquitin-specific protease activity

Known as: deubiquitinase, UBP, ubiquitin-specific protease activity 
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. [GOC:jh2, ISBN… 
National Institutes of Health

Related topics

Related topics

4 relations
Deubiquitinating Enzymesubiquitin-specific protease

Broader (2)

Deubiquitinationubiquitinyl hydrolase activity

Papers overview

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2018
2018
Inhibition of the Deubiquitinase Usp14 Diminishes Direct MHC Class I Antigen Presentation
Infected or transformed cells must present peptides derived from endogenous proteins on MHC class I molecules to be recognized… 
2017
2017
miR-197-3p-induced downregulation of lysine 63 deubiquitinase promotes cell proliferation and inhibits cell apoptosis in lung adenocarcinoma cell lines
Lung adenocarcinoma (LUAD) is a common cause of cancer-associated mortality. The dysregulation of microRNA (miR) expression has… 
2016
2016
Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module
ABSTRACT The SAGA complex contains two enzymatic modules, which house histone acetyltransferase (HAT) and deubiquitinase (DUB… 
2015
2015
Targeting of the deubiquitinase USP9X attenuates B-cell acute lymphoblastic leukemia cell survival and overcomes glucocorticoid resistance.
2015
2015
Dynamics of an Active-Site Flap Contributes to Catalysis in a JAMM Family Metallo Deubiquitinase.
The endosome-associated deubiquitinase (DUB) AMSH is a member of the JAMM family of zinc-dependent metallo isopeptidases with… 
2014
2014
E1‐Catalyzed Ubiquitin C‐Terminal Amidation for the Facile Synthesis of Deubiquitinase Substrates
Will Ub my partner? The ubiquitin (Ub)-activating enzyme (E1) was used to catalyze an amidation reaction to functionalize the C… 
2013
2013
High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity.
Review
2007
Review
2007
CYLD: A Multifunctional Deubiquitinase
The nuclear factor-kappaB (NF-κB) and c-Jun NH2-terminal kinase (JNK) signaling pathways regulate diverse biological processes… 
1999
1999
Upper body power comparison between groups of cross-country skiers and runners.
The purpose of this study was to evaluate relationships between upper body power (UBP) and cross-country ski skating race… 
1993
1993
Evidence that a neutral cholesteryl ester hydrolase is responsible for the extralysosomal hydrolysis of high‐density lipoprotein cholesteryl ester in rat hepatoma cells (Fu5AH)
Diethylumbelliferyl phosphate (UBP) has been shown to inhibit the neutral cholesteryl ester hydrolase activity responsible for… 
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