ubiquilin

 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
C9ORF72-hexanucleotide repeat expansions and ubiquilin-2 (UBQLN2) mutations are recently identified genetic markers in… (More)
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2012
2012
Amyotrophic lateral sclerosis (ALS) shows clinical and pathological overlap with frontotemporal dementia that includes the… (More)
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Highly Cited
2011
Highly Cited
2011
Amyotrophic lateral sclerosis (ALS) is a paralytic and usually fatal disorder caused by motor-neuron degeneration in the brain… (More)
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Highly Cited
2010
Highly Cited
2010
Autophagy is the process by which organelles and portions of the cytoplasm are degraded in lysosomes. Several different forms of… (More)
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Highly Cited
2010
Highly Cited
2010
TDP-43 (43-kDa TAR DNA-binding protein) is a major constituent of ubiquitin-positive cytosolic aggregates present in neurons of… (More)
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Highly Cited
2009
Highly Cited
2009
Unwanted proteins in the endoplasmic reticulum (ER) are exported into the cytoplasm and degraded by the proteasome through the ER… (More)
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2006
2006
Ubiquilin 1 (UBQLN1) is a ubiquitin-like protein, which has been shown to play a central role in regulating the proteasomal… (More)
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2006
2006
Expanded polyglutamine (polyQ) tracts are associated with the induction of protein aggregation and cause cytotoxicity in nine… (More)
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Highly Cited
2004
Highly Cited
2004
Mammalian cells acquire tolerance against multiple stressors through the high-level expression of stress-responsible genes. We… (More)
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Highly Cited
2000
Highly Cited
2000
Mutations in the highly homologous presenilin genes encoding presenilin-1 and presenilin-2 (PS1 and PS2) are linked to early… (More)
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