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ubiquilin

 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Summary We investigated how mitochondrial membrane proteins remain soluble in the cytosol until their delivery to mitochondria or… Expand
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Highly Cited
2012
Highly Cited
2012
C9ORF72-hexanucleotide repeat expansions and ubiquilin-2 (UBQLN2) mutations are recently identified genetic markers in… Expand
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Highly Cited
2012
Highly Cited
2012
Amyotrophic lateral sclerosis (ALS) shows clinical and pathological overlap with frontotemporal dementia that includes the… Expand
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Highly Cited
2011
Highly Cited
2011
Amyotrophic lateral sclerosis (ALS) is a paralytic and usually fatal disorder caused by motor-neuron degeneration in the brain… Expand
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Highly Cited
2011
Highly Cited
2011
Background: Ubiquilin-1 may contribute to the development of Alzheimer disease; however, the mechanisms are unclear. Results… Expand
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Highly Cited
2010
Highly Cited
2010
Autophagy is the process by which organelles and portions of the cytoplasm are degraded in lysosomes. Several different forms of… Expand
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Highly Cited
2010
Highly Cited
2010
TDP-43 (43-kDa TAR DNA-binding protein) is a major constituent of ubiquitin-positive cytosolic aggregates present in neurons of… Expand
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Highly Cited
2009
Highly Cited
2009
Loss of ubiquilin or erasin activates ER stress, increases accumulation of polyubiquitinated proteins, and shortens lifespan in… Expand
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Highly Cited
2009
Highly Cited
2009
TDP-43 (43-kDa TAR DNA-binding domain protein) is a major constituent of ubiquitin-positive cytoplasmic aggregates present in… Expand
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Highly Cited
2004
Highly Cited
2004
Mammalian cells acquire tolerance against multiple stressors through the high‐level expression of stress‐responsible genes. We… Expand
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