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tumor necrosis factor production

Known as: TNF production, TNF-alpha production, tumor necrosis factor-alpha production 
The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular… 
National Institutes of Health

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tumor necrosis factor biosynthetic processtumor necrosis factor secretion

Papers overview

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Highly Cited
2007
Highly Cited
2007
Macrophage-Elicited Osteoclastogenesis in Response to Bacterial Stimulation Requires Toll-Like Receptor 2-Dependent Tumor Necrosis Factor-Alpha Production
ABSTRACT The receptor activator of NF-κB ligand (RANKL) and the proinflammatory cytokines are believed to play important roles in… 
Highly Cited
1998
Highly Cited
1998
Increase in tumor necrosis factor‐α production linked to the toxicity of indomethacin for the rat small intestine
1 The toxic effects of nonsteroidal anti‐inflammatory drugs for the lower gastrointestinal tract share certain features with… 
Highly Cited
1997
Highly Cited
1997
Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat.
The inflammatory cytokines interleukin (IL) 1 and tumor necrosis factor (TNF) may play an important role in hepatic ischemia… 
Highly Cited
1997
Highly Cited
1997
A Leishmania protein that modulates interleukin (IL)‐12, IL‐10 and tumor necrosis factor‐α production and expression of B7‐1 in human monocyte‐derived antigen‐presenting cells
LeIF, a gene homologue of the eukaryotic initiation factor 4A was first described as a leishmanial antigen that induced a Th1… 
Highly Cited
1997
Highly Cited
1997
Nitric Oxide Increases Tumor Necrosis Factor Production in Differentiated U937 Cells by Decreasing Cyclic AMP*
Nitric oxide (NO) increases tumor necrosis factor (TNF) synthesis in human peripheral blood mononuclear cells by a cGMP… 
Highly Cited
1994
Highly Cited
1994
Recombinant soluble CD14 inhibits LPS-induced tumor necrosis factor-alpha production by cells in whole blood.
CD14 functions as a cell surface receptor for LPS in the activation of monocytes/macrophages and neutrophils by endotoxin. To… 
Highly Cited
1993
Highly Cited
1993
The release of endotoxin from antibiotic-treated Escherichia coli and the production of tumour necrosis factor by human monocytes.
The influence of antibiotic-induced release of endotoxin from in-vitro grown Escherichia coli on the production of tumour… 
Highly Cited
1993
Highly Cited
1993
Mechanism of increased tumor necrosis factor production after thermal injury. Altered sensitivity to PGE2 and immunomodulation with indomethacin.
Altered macrophage function after thermal injury is associated with increased production of PGE2 and TNF. However, it is not… 
Highly Cited
1993
Highly Cited
1993
Augmentation of murine tumor necrosis factor production by amphotericin B in vitro and in vivo
Murine peritoneal macrophages were preincubated with amphotericin B (AMPH) and were then stimulated with bacterial… 
Highly Cited
1992
Highly Cited
1992
Gangliosides suppress tumor necrosis factor production in human monocytes.
Both normal and malignant cells contain gangliosides as important cell membrane constituents that, after being shed, may… 
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