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tryprostatin B

National Institutes of Health

Papers overview

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2019
2019
A concise and efficient total synthesis of microtubule inhibitor tryprostatin B (1) is described. The key step is the preparation… 
2018
2018
Prenylation of cyclodipeptides contributes largely to the structure diversification and biological activity. The prenylated… 
2017
2017
FtmPT1 is a fungal indole prenyltransferase that affords Tryprostatin B from Brevianamide F and dimethylallyl pyrophosphate… 
2015
2015
In the first part of this work, binding energies, inhibition constants and binding modes for a group of previously synthesized… 
2003
2003
Tryprostatin B was synthesized in 32% overall yield from the readily available dipeptide anhydride cyclo-(l-Trp-l-Pro). Its…