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tropomyosin-related kinase-B, human

Known as: TrkB protein, human, Tropomyosin-Related Kinase B, NTRK2 protein, human 
BDNF/NT-3 growth factors receptor (822 aa, ~92 kDa) is encoded by the human NTRK2 gene. This protein plays a role in growth factor-dependent… 
National Institutes of Health

Related topics

Related topics

26 relations
Cell Differentiation processCell ProliferationEnzyme GeneImmunoglobulin C2-set Domain

Broader (2)

Membrane GlycoproteinsProtein Tyrosine Kinase

Papers overview

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Highly Cited
2007
Highly Cited
2007
Inhibition of PTEN by peroxynitrite activates the phosphoinositide‐3‐kinase/Akt neuroprotective signaling pathway
Peroxynitrite is usually considered as a neurotoxic nitric oxide‐derivative. However, an increasing body of evidence suggests… 
Highly Cited
2003
Highly Cited
2003
Distribution and colocalization of NGF and GDNF family ligand receptor mRNAs in dorsal root and nodose ganglion neurons of adult rats.
Highly Cited
2002
Highly Cited
2002
Dynamic patterns of BDNF expression in injured sensory neurons: differential modulation by NGF and NT‐3
It has been suggested that altered retrograde neurotrophin support contributes to the phenotypic switch observed in BDNF… 
Highly Cited
1998
Highly Cited
1998
Expression of brain‐derived neurotrophic factor protein in activated microglia of human immunodeficiency virus type 1 encephalitis
The role of neurotrophic factors and their therapeutic potential have been investigated in various neurodegenerative disorders… 
Highly Cited
1998
Highly Cited
1998
Effect of ethanol on neurotrophin-mediated cell survival and receptor expression in cultures of cortical neurons.
Review
1996
Review
1996
Neurotrophins Cause a New Sensation
Highly Cited
1996
Highly Cited
1996
Basophil priming by neurotrophic factors. Activation through the trk receptor.
There is increasing evidence that nerve growth factor (NGF) acts on cells of the immune system, apart from its neurotrophic… 
Highly Cited
1995
Highly Cited
1995
Interaction with TrkA Immobilizes gp75 in the High Affinity Nerve Growth Factor Receptor Complex (*)
It has been proposed that the high affinity nerve growth factor (NGF) receptor required for NGF response is a complex of two… 
Highly Cited
1993
Highly Cited
1993
Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system
Highly Cited
1993
Highly Cited
1993
BDNF and trkB mRNA expression in the hippocampal formation of aging rats
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