tropomyosin-related kinase-B, human

Known as: TrkB protein, human, Tropomyosin-Related Kinase B, NTRK2 protein, human 
BDNF/NT-3 growth factors receptor (822 aa, ~92 kDa) is encoded by the human NTRK2 gene. This protein plays a role in growth factor-dependent… (More)
National Institutes of Health

Related topics

Related topics

26 relations
Cell Differentiation processCell ProliferationEnzyme GeneImmunoglobulin C2-set Domain
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Broader (2)

Membrane GlycoproteinsProtein Tyrosine Kinase

Papers overview

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Review
2017
Review
2017
BDNF and Hippocampal Synaptic Plasticity.
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that also include nerve growth factor… (More)
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Review
2017
Review
2017
Brain-derived neurotrophic factor in mood disorders and antidepressant treatments
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of depressed patients and at least the… (More)
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2013
2013
Brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer
Background:Brain-derived neutrophic factor (BDNF) is a member of the neutrophin family that is known to activate the high… (More)
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Highly Cited
2009
Highly Cited
2009
Tropomyosin-Related Kinase B in the Mesolimbic Dopamine System: Region-Specific Effects on Cocaine Reward
BACKGROUND Previous studies found that brain-derived neurotrophic factor (BDNF) derived from nucleus accumbens (NAc) neurons can… (More)
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Review
2006
Review
2006
Neurotrophin-regulated signalling pathways.
Neurotrophins are a family of closely related proteins that were identified initially as survival factors for sensory and… (More)
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Highly Cited
2002
Highly Cited
2002
Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity.
We have investigated potential mechanisms by which exercise can promote changes in neuronal plasticity via modulation of… (More)
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Highly Cited
1998
Highly Cited
1998
BDNF Has Opposite Effects on the Quantal Amplitude of Pyramidal Neuron and Interneuron Excitatory Synapses
Recently, we have identified a novel form of synaptic plasticity that acts to stabilize neocortical firing rates by scaling the… (More)
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Highly Cited
1991
Highly Cited
1991
The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3.
trkB is a tyrosine protein kinase gene highly related to trk, a proto-oncogene that encodes a receptor for nerve growth factor… (More)
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Highly Cited
1991
Highly Cited
1991
trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.
We have screened an adult rat cerebellar cDNA library in search of novel protein tyrosine-kinase (PTK) cDNAs. A cDNA for a… (More)
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Highly Cited
1990
Highly Cited
1990
The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain.
We previously identified two tyrosine protein kinase genes, designated trk and trkB, that code for putative neurogenic cell… (More)
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