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tropinesterase

Known as: atropinase, atropine esterase, atropinesterase 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Carboxylic Ester Hydrolases

Papers overview

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2010
2010
High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma.
S-hyoscyamine (S-hyo) is a toxic tropane alkaloid from plants of the solanacea family, which is extracted for pharmaceutical… Expand
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2010
2010
LC-ESI MS/MS quantification of atropine and six other antimuscarinic tropane alkaloids in plasma
We have developed and validated a quantitative liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI MS… Expand
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Highly Cited
1994
Highly Cited
1994
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
This study compared the efficacy of HI6 and 2-PAM against nerve agent (soman, tabun, sarin, and VX)-induced lethality in the… Expand
1985
1985
P NMR and mass spectrometry of atropinesterase and some serine proteases phosphorylated with a transition-state analogue.
The serine residue in the active center of atropinesterase (AtrE), alpha-chymotrypsin (Chymo), and subtilisin A (Sub) and in… Expand
1983
1983
The primary structure of atropinesterase from Pseudomonas putida
 
Highly Cited
1976
Highly Cited
1976
Iris pigmentation and atropine mydriasis.
The experiments were designed to study the well-known pigment-dependent mydriatic effect of atropine in the eye. In vitro… Expand
1976
1976
An explanation for the long duration of mydriatic effect of atropine in eye.
The mydriatic effect of topically applied 3H-atropine (2%) was compared in the pigmented rabbits (black fur and dark brown irides… Expand
1974
1974
Genetic polymorphism of plasma carboxylesterases in the rabbit: correlation with pharmacologic and toxicologic effects.
Abstract An enzyme that degrades atropine is found in varying frequency in the sera and tissues of rabbits. Its presence or… Expand
1963
1963
PURIFICATION AND CHARACTERIZATION OF A GENETICALLY DETERMINED RABBIT SERUM ESTERASE.
The destruction of atropine (nn-hyoscyamine) was first reported by Fleischmann over 50 years ago (1). Subsequently, it was… Expand
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Highly Cited
1943
Highly Cited
1943
Atropinesterase, a Genetically Determined Enzyme in the Rabbit.
 
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