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trimegestone

Known as: 17-(2-hydroxy-1-oxopropyl)-17-methylestra-4,9-dien-3-one, 21-hydroxypromegestone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Promegestone

Narrower (2)

RU-27987RU-27988
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Inhibitors and activation markers of the haemostatic system during hormone therapy: A comparative study of oral estradiol (2 mg)/ dydrogesterone and estradiol (2 mg)/ trimegestone
Summary Epidemiological studies have shown that hormone therapy (HT) increases the risk of venous thromboembolism in post… 
2008
2008
Pharmacological profile of progestins.
The synthetic progestins used so far for contraception and menopausal hormone therapy are derived either from testosterone (19… 
2005
2005
Differential effects of estrogens and progestins on the anticoagulant tissue factor pathway inhibitor in the rat
2004
2004
Randomized trial of effects of estradiol in combination with either norethisterone acetate or trimegestone on lipids and lipoproteins in postmenopausal women
Objective This double-blind, randomized, multicenter study was designed to compare the blood lipid profiles in postmenopausal… 
2002
2002
Assessment of the metabolic tolerance in postmenopausal women over a 1-year period of two hormone replacement therapies containing estradiol in combination with either norgestrel or trimegestone
This double-blind, randomized, multi-center study compared the metabolic tolerance of a combined formulation containing estradiol… 
2001
2001
Effects of 17β-estradiol and trimegestone alone ,and in combination ,on the bone and uterus of ovariectomized rats
Trimegestone is a novel norpregnane progestin ,which is being developed ,in combination with 17β-estradiol ,for the treatment of… 
2001
2001
Rat uterine complement C3 expression as a model for progesterone receptor modulators: characterization of the new progestin trimegestone
2001
2001
Effect of trimegestone alone or in combination with estradiol on bone mass and bone turnover in an adult rat model of osteopenia
The effects of trimegestone (1 mg/kg/day orally) ,a novel norpregnane progestin ,and 17β-estradiol (10 g/kg/day subcutaneously… 
Highly Cited
2000
Highly Cited
2000
In vitro characterization of trimegestone: a new potent and selective progestin
1999
1999
Acceptability and patterns of uterine bleeding in sequential trimegestone-based hormone replacement therapy: a dose-ranging study.
Trimegestone is a norpregnane progestogen which is being developed in combination with oral oestradiol as postmenopausal hormone… 
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