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To confirm recent in vitro findings, we examined the cardiovascular and electrocardiographic (ECG) effects of the dopamine… Expand Ibutilide is a ‘pure’ class III antiarrhythmic drug, used intravenously against atrial flutter and fibrillation. At a cellular… Expand There have been extensive efforts to develop I(Kr) channel blockers as a new antiarrhythmic agent for atrial or ventricular… Expand In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular… Expand The Next Generation of Antiarrhythmic Drugs. Five drugs currently constitute approximately 70% of the world market for… Expand Two high-performance liquid chromatography (HPLC) methods were developed for the determination of trecetilide in plasma samples… Expand