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transplatin

Known as: trans-DDP, trans-diamminedichloroplatinum II, trans-dichlorodiammineplatinum II 
National Institutes of Health

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2 relations

Broader (2)

CisplatinCross-Linking Reagents

Papers overview

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2017
2017
Transplatin derivatives as anticancer agents
2014
2014
The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands
Oligonucleotides modified by clinically ineffective trans-diamminedichloridoplatinum(II) (transplatin) have been shown to be… 
2014
2014
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
  • 2014
  • Corpus ID: 204890501
http://dx.doi.org/10.1016/j.saa.2014.08.154 1386-1425/ 2014 Published by Elsevier B.V. As researchers in the field of Pt(II) and… 
2014
2014
Synthesis, characterization, and biological activity of platinum II, III, and IV pivaloamidine complexes
Imino ligands have proven to be able to activate the trans geometry of platinum(II) complexes towards antitumor activity. These… 
2010
2010
Differential transport of platinum compounds by the human organic cation transporter
Background: Solute carriers (SLCs), in particular organic cation transporters (OCTs), have been implicated in the cellular uptake… 
2009
2009
Hydrolysis Mechanism of New Anticancer Drug Transplatin Analogues Containing One Nonplanar Heterocyclic Amine Ligand
Hydrolysis processes of novel anticancer transplatin analogues,trans-[PtCl2(NH3)(Am)](Am:nonplanar heterocycle piperidine or… 
2006
2006
Metabolism in Male and Female Rats Differentially Alter Hepatic Drug and Steroid Hormone Platinum Anticancer Drugs Modulate P-450 mRNA Levels and Updated
Treatment of male rats with the anticancer drug cisplatin leads to feminization of the profile of cytochromes P-450 and other… 
2001
2001
OLIGONUCLEOTIDES MODIFIEDWITH TRANSPLATIN DERIVATIVES: FASTAND EFFICIENTMETALLORIBOZYMES
When an oligonucleotide containing a 1,3-(G,G)-transplatin cross-link at a GNG site (N represents a C, T, A or U residue) is… 
2000
2000
Interaction between Actin and Cisplatin or Transplatin
Highly Cited
1986
Highly Cited
1986
Enhancement of natural killer cytotoxicity by cis-diamminedichloroplatinum (II) in vivo and in vitro.
To investigate the immunomodulating properties of cis-diamminedichloroplatinum (II) (CDDP), we studied the drug's effects on… 
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