transplatin

Known as: trans-DDP, trans-diamminedichloroplatinum II, trans-dichlorodiammineplatinum II 
 
National Institutes of Health

Papers overview

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2009
2009
Human metallothioneins, small cysteine- and metal-rich proteins, play an important role in the acquired resistance to platinum… (More)
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2006
2006
It is well-known that although cisplatin, [cis-[PtCl2(NH3)2], is an anticancer drug, its isomer transplatin is not cytotoxic… (More)
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Highly Cited
2004
Highly Cited
2004
The NH2-terminal Jun kinases (JNKs) function in diverse roles through phosphorylation and activation of AP-1 components including… (More)
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Highly Cited
2003
Highly Cited
2003
The activating transcription factor 2 (ATF2) is a member of the ATF/cAMP-response element-binding protein family of basic-leucine… (More)
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Highly Cited
2001
Highly Cited
2001
Microarrays are a new technology used to study global gene expression and to decipher biological pathways. In the current study… (More)
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Highly Cited
2000
Highly Cited
2000
We studied the roles of the phosphatidylinositol 3-kinase (PI-3K)-protein kinase B/Akt-BAD cascade in both cisplatin-resistant… (More)
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Highly Cited
1999
Highly Cited
1999
Cisplatin treatment activates multiple signal transduction pathways, which can lead to several cellular responses including cell… (More)
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Highly Cited
1999
Highly Cited
1999
We have studied the roles of c-Jun N-terminal protein kinase (JNK) and extracellular signal-regulated protein kinase (ERK… (More)
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Highly Cited
1997
Highly Cited
1997
We have studied the role of Jun/stress-activated protein kinase (JNK/SAPK) pathway in DNA repair and cisplatin resistance in T98G… (More)
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1990
1990
The present study was designed to compare the nephrotoxicity induced by the three platinum compounds cisplatin (CDDP… (More)
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