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transplatin

Known as: trans-DDP, trans-diamminedichloroplatinum II, trans-dichlorodiammineplatinum II 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CisplatinCross-Linking Reagents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance.
Clinically ineffective transplatin was converted into a photosensitive prodrug for drug delivery and triggered release to… 
2009
2009
Reaction of human metallothionein-3 with cisplatin and transplatin
Human metallothioneins, small cysteine- and metal-rich proteins, play an important role in the acquired resistance to platinum… 
Highly Cited
2007
Highly Cited
2007
ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme.
The interactions of cisplatin and its analogues, transplatin, carboplatin and oxaliplatin, with hen egg white lysozyme were… 
Highly Cited
2006
Highly Cited
2006
Transplatin is cytotoxic when photoactivated: enhanced formation of DNA cross-links.
It is well-known that although cisplatin, [cis-[PtCl2(NH3)2], is an anticancer drug, its isomer transplatin is not cytotoxic… 
2004
2004
DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
Highly Cited
2000
Highly Cited
2000
CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin
Treatment of cells with cisplatin induces a sustained activation of the stress activated protein kinase SAPK/JNK and the mitogen… 
1998
1998
DNA sequence selectivity of cisplatin analogues in intact human cells.
1997
1997
Interaction of 11 cisplatin analogues with DNA: characteristic pattern of damage with monofunctional analogues.
1996
1996
Interstrand cross-linking reaction in triplexes containing a monofunctional transplatin-adduct.
Our aim was to determine whether a single transplatin monofunctional adduct, either trans-[Pt(NH3)2(dC)Cl]+ or trans-[Pt(NH3)2(dG… 
Highly Cited
1987
Highly Cited
1987
Cisplatin nephrotoxicity: in vitro studies with precision-cut rabbit renal cortical slices.
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