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trandolaprilat

Known as: 1-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid, trandolaprilate 
A non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Trandolaprilat competitively binds to and inhibits ACE… 
National Institutes of Health

Related topics

Related topics

5 relations
24 HR trandolapril 2 MG / Verapamil hydrochloride 180 MG Extended Release Oral Tablet [Tarka]24 HR trandolapril 2 MG / Verapamil hydrochloride 240 MG Extended Release Oral Tablet

Broader (2)

Indolestrandolapril

Narrower (1)

RU 44 403

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Simultaneous determination of ramipril, ramiprilat and telmisartan in human plasma using liquid chromatography tandem mass spectrometry.
Highly Cited
2009
Highly Cited
2009
Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.
Review
2003
Review
2003
Trandolapril: a newer angiotensin-converting enzyme inhibitor.
Highly Cited
1998
Highly Cited
1998
The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance--distinct enzymic characteristics and alternative expression during pupal development.
Drosophila melanogaster express two distinct angiotensin-I-converting enzymes (ACEs) called Ance and Acer, which display a high… 
Highly Cited
1995
Highly Cited
1995
Cloning and Expression of an Evolutionary Conserved Single-domain Angiotensin Converting Enzyme from Drosophila melanogaster(*)
Mammalian somatic angiotensin converting enzyme (EC 3.4.15.1, ACE) consists of two highly homologous (N- and C-) domains encoded… 
Highly Cited
1994
Highly Cited
1994
Identification of two active site residues in human angiotensin I-converting enzyme.
Review
1993
Review
1993
Pharmacologic profile of trandolapril, a new angiotensin-converting enzyme inhibitor.
Highly Cited
1992
Highly Cited
1992
The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.
1992
1992
Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells.
An increase in cell size and protein content was observed when quiescent arterial smooth muscle cells in culture were incubated… 
Review
1992
Review
1992
Trandolapril in hypertension: overview of a new angiotensin-converting enzyme inhibitor.
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