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toxin biosynthetic process

Known as: toxin anabolism, toxin synthesis, toxin biosynthesis 
The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Clostridium difficile toxin synthesis is negatively regulated by TcdC.
Clostridium difficile toxin synthesis is growth phase-dependent and is regulated by various environmental signals. The toxin… Expand
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Highly Cited
2007
Highly Cited
2007
Clostridium difficile toxin expression is inhibited by the novel regulator TcdC
Clostridium difficile, an emerging nosocomial pathogen of increasing clinical significance, produces two large protein toxins… Expand
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Highly Cited
2005
Highly Cited
2005
Emetic toxin formation of Bacillus cereus is restricted to a single evolutionary lineage of closely related strains.
An in-depth polyphasic approach was applied to study the population structure of the human pathogen Bacillus cereus. To assess… Expand
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Review
2004
Review
2004
Bacillus cereus, the causative agent of an emetic type of food-borne illness.
Bacillus cereus is the causative agent of two distinct forms of gastroenteritic disease connected to food-poisoning. It produces… Expand
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Highly Cited
2001
Highly Cited
2001
Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor
  • N. Mani, B. Dupuy
  • Proceedings of the National Academy of Sciences…
  • 2001
    • Corpus ID: 28508297
Clostridium difficile, a causative agent of antibiotic-associated diarrhea and its potentially lethal form, pseudomembranous… Expand
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Highly Cited
2001
Highly Cited
2001
A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum.
The trichothecenes T-2 toxin and deoxynivalenol (DON) are natural fungal products that are toxic to both animals and plants… Expand
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Review
1999
Review
1999
Pseudomonas syringae Phytotoxins: Mode of Action, Regulation, and Biosynthesis by Peptide and Polyketide Synthetases
SUMMARY Coronatine, syringomycin, syringopeptin, tabtoxin, and phaseolotoxin are the most intensively studied phytotoxins of… Expand
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Highly Cited
1999
Highly Cited
1999
TRI12, a trichothecene efflux pump from Fusarium sporotrichioides: gene isolation and expression in yeast
Abstract Many of the genes involved in trichothecene toxin biosynthesis in Fusarium sporotrichioides are present within a gene… Expand
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Review
1992
Review
1992
Structural and functional relationships among the RTX toxin determinants of gram-negative bacteria.
  • J. Coote
  • FEMS microbiology reviews
  • 1992
    • Corpus ID: 36968033
The RTX (repeats in toxin) cytolytic toxins represent a family of important virulence factors that have disseminated widely among… Expand
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Highly Cited
1988
Highly Cited
1988
DNA probes for Shiga-like toxins I and II and for toxin-converting bacteriophages.
A set of DNA probes has been developed to study the genes for Shiga-like toxins (SLT) and the bacteriophage from which these… Expand
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