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torsemide

Known as: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, Torasemidum, 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea 
An anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES This individually randomized, open-label, parallel-group pilot study was designed to test the hypothesis that the… Expand
Highly Cited
2004
Highly Cited
2004
Human CYP2C9 is important in the metabolism of numerous clinically used drugs such as the anticoagulant warfarin, the… Expand
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Highly Cited
2002
Highly Cited
2002
Diuretics such as torasemide are commonly used to treat chronic heart failure (CHF). 
Highly Cited
2001
Highly Cited
2001
PURPOSE Because the bioavailability of oral furosemide is erratic and often incomplete, we tested the hypothesis that patients… Expand
Highly Cited
1999
Highly Cited
1999
Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as phenytoin, S-warfarin, tolbutamide, losartan… Expand
Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Studies on the role of loop diuretics in patients with acute renal failure (ARF) are largely retrospective, anecdotal… Expand
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Highly Cited
1995
Highly Cited
1995
The bioavailability, pharmacokinetics, and pharmacodynamics of torsemide (10 mg orally and intravenously) and furosemide (40 mg… Expand
Highly Cited
1994
Highly Cited
1994
It is commonly assumed that thiazide diuretics are ineffective in patients with advanced renal failure (GFR < 30 ml/min/1.73 m2… Expand