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torsemide

Known as: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, Torasemidum, 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea 
An anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (4)

Antihypertensive AgentsDiureticsSodium Potassium Chloride Symporter InhibitorsSulfonamides
AnuriaCYP2C8 protein, humanCYP2C9 protein, humanCongestive heart failure

Narrower (1)

Luprac

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo.
Brain edema and derived oxidative stress potentially are critical events in the hippocampal-entorhinal cortical (HEC… 
2009
2009
Beneficial Effects of Torasemide on Systolic Wall Stress and Sympathetic Nervous Activity in Asymptomatic or Mildly Symptomatic Patients With Heart Failure: Comparison With Azosemide
Loop diuretics could adversely influence prognosis due to activation of neurohumoral mechanism in the long term. Previous study… 
2008
2008
The Polymorphisms Asn130Asp and Val174Ala in OATP1B1 and the CYP2C9 Allele *3 Independently Affect Torsemide Pharmacokinetics and Pharmacodynamics
To the editor: We investigated two organic anion transporting polypeptide 1B1 (OATP1B1) polymorphisms in relation to torsemide… 
Highly Cited
2005
Highly Cited
2005
Electrochemical characterisation of the human cytochrome P450 CYP2C9.
2002
2002
Crystal forms of torasemide: new insights.
Review
1994
Review
1994
Pharmacological classification and renal actions of diuretics.
Diuretics may be classified according to their chemical structure, their mechanism and site of action within the nephron, and… 
1993
1993
Swelling of glial cells in lactacidosis and by glutamate: significance of Cl—-transport
1992
1992
Effect of inhaled furosemide and torasemide on bronchial response to ultrasonically nebulized distilled water in asthmatic subjects.
Inhaled furosemide has been shown to reduce the bronchoconstriction induced by several indirect stimuli, including ultrasonically… 
Review
1992
Review
1992
Clinical pharmacology of loop diuretics in health and disease.
There are differences in metabolism and excretion of the loop diuretics which extrapolate to differences in pharmacokinetic… 
1987
1987
Chloride transport blockers inhibit the chloride-dependent glutamate binding to rat brain membranes
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