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torsemide

Known as: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, Torasemidum, 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea 
An anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop… 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Because of its dynamic nature, the composition and structure of the myocardial collagen network can be reversibly modified to… 
Review
2009
Review
2009
Cytochrome P450 2C9 (CYP2C9) is one of the most abundant CYP enzymes in the human liver. CYP2C9 metabolizes more than 100… 
Highly Cited
2004
Highly Cited
2004
Human CYP2C9 is important in the metabolism of numerous clinically used drugs such as the anticoagulant warfarin, the… 
Highly Cited
2002
Highly Cited
2002
Highly Cited
1999
Highly Cited
1999
Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as phenytoin, S-warfarin, tolbutamide, losartan… 
Review
1999
Review
1999
Liver disease can modify the kinetics of drugs biotransformed by the liver. This review updates recent developments in this field… 
Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… 
Highly Cited
1997
Highly Cited
1997
BACKGROUND Studies on the role of loop diuretics in patients with acute renal failure (ARF) are largely retrospective, anecdotal… 
Highly Cited
1994
Highly Cited
1994
It is commonly assumed that thiazide diuretics are ineffective in patients with advanced renal failure (GFR < 30 ml/min/1.73 m2…