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tolrestat

Known as: N-((5-(trifluoromethyl)-6-methoxy-1-naphthalenyl)thioxomethyl)-N-methylglycine, N-5-trifluoromethyl-6-methoxy-1-thionaphthoyl-N-methylglycine, Glycine, N-((6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)thioxomethyl)-N-methyl- 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

AY 27773

Broader (2)

Enzyme InhibitorsNaphthalenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Aldose reductase regulates TNF‐α‐induced cell signaling and apoptosis in vascular endothelial cells
2001
2001
Involvement of aldose reductase in the metabolism of atherogenic aldehydes.
Highly Cited
1990
Highly Cited
1990
Diabetes-related histopathologies of the rat retina prevented with an aldose reductase inhibitor.
1990
1990
Inhibition kinetics of human kidney aldose and aldehyde reductases by aldose reductase inhibitors.
1990
1990
Increase in aldose reductase mRNA in dog lens epithelial cells under hypertonic conditions.
1988
1988
Aldose reductase and retinal capillary basement membrane thickening.
1988
1988
Purification of aldose reductase from human placenta and stabilization of the inhibitor binding site.
1987
1987
Tolrestat, an Aldose Reductase Inhibitor, Prevents Nerve Dysfunction in Conscious Diabetic Rats
The effect of 4 wk of streptozocin (STZ)-induced diabetes on the transmission time of the auditory-evoked brain stem response… 
Highly Cited
1986
Highly Cited
1986
Prevention of Basement Membrane Thickening in Retinal Capillaries by a Novel Inhibitor of Aldose Reductase, Tolrestat
A diabetic-like thickening of retinal capillary basement membranes induced in rats fed for 207 consecutive days a diet containing… 
1985
1985
Prevention of Cataract Development in Severely Galactosemic Rats by the Aldose Reductase Inhibitor, Tolrestat
Abstract With a fixed time period of galactose feeding, the rate of appearance of lenticular opacities depended on the severity… 
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