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tolrestat
Known as:
N-((5-(trifluoromethyl)-6-methoxy-1-naphthalenyl)thioxomethyl)-N-methylglycine
, N-5-trifluoromethyl-6-methoxy-1-thionaphthoyl-N-methylglycine
, Glycine, N-((6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)thioxomethyl)-N-methyl-
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National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
AY 27773
Broader (2)
Enzyme Inhibitors
Naphthalenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
In silico designing of novel inhibitors for triple inhibition of Aldose Reductase, Aldose Reductase like protein 1, and Aldehyde Reductase.
Arpita Devi
Current Computer - Aided Drug Design
2019
Corpus ID: 208216278
Cancer is a well-known and well-studied disease. There are environmental as well as genetic factors that trigger cancer. All…
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2017
2017
United States Patent ( 19 ) Notvest ( 54 ) TOLRESTAT FOR HEARING IMPAIRMENT 75 Inventor :
R. R. Notvest
,
F. Routh
2017
Corpus ID: 145042045
(56) References Cited U.S. PATENT DOCUMENTS 4,568,693 2/1986 Sestans ................................ 514/524 OTHER PUBLICATIONS…
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2016
2016
Identifikasi Agen Antidiabetes Melalui Jalur Penghambatan Aldose Reductase Menggunakan Pyrxdengan Empat Algoritma Molecular Docking
Agus Maulana
,
K. Wulansari
,
Devy Anwar Zhelsiana
,
Wiwin Sri Sulasmi
,
Broto Santoso
2016
Corpus ID: 90371315
Aldosereductaseisaldo-ketoreductaseenzymethatconvertglucoseto sorbitol andfructosebypolyolpathway. Accumulationof sorbitol…
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2003
2003
Zacma u psow w przebiegu cukrzycy
J. Madany
2003
Corpus ID: 68942628
The aim of this study was to establish the characteristic cataract changes that occur in diabetic dogs. Research was conducted on…
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2000
2000
EFFECT OF TOLRESTAT ON HIGH GLUCOSE-INDUCED ACTIN DISASSEMBLY IN GLOMERULAR MESANGIAL CELLS
Zhou Xiao
2000
Corpus ID: 87193208
The effect of Tolrestat, an aldose reductase inhibitor,on high glucose-induced actin disassembly in rat glomerular mesangial…
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1995
1995
The Italian Multicentre Surveillance Study
C. Coscelli
,
D. Cucinotta
,
F. Santeusanio
,
D. Fedele
1995
Corpus ID: 78809064
Summary This was a surveillance study to evaluate the safety of tolrestat (200 mg/day) in the treatment of diabetic neuropathy…
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1995
1995
Pharmacokinetic interaction between aspirin and tolrestat in normal volunteers
V. Garg
,
V. Parker
,
+4 authors
S. Chiang
1995
Corpus ID: 86414790
1986
1986
Disposition of /sup 14/C tolrestat in laboratory animals and man
E. Ferdinandi
,
D. Hicks
,
M. Cayen
1986
Corpus ID: 87316020
The disposition of the aldose reductase inhibitor tolrestat (T) was determined in the mouse, rat, dog, assemensis monkey, and man…
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1984
1984
Determination of Tolrestat, a Novel Aldose Reductase Inhibitor, in Serum and Tissues
D. Hicks
,
M. Kraml
Therapeutic Drug Monitoring
1984
Corpus ID: 2617857
Summary: An ultraviolet spectrophotometric method and a high-performance liquid chromatographic (HPLC) method were developed for…
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