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tizanidine hydrochloride

Known as: 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-, Monohydrochloride, tizanidine monohydrochloride, 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole Hydrochloride 
The hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant… 
National Institutes of Health

Related topics

Related topics

13 relations
Adrenergic alpha2-Agonists [MoA]Drug AllergyLow Back PainMuscle Cramp

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Zanaflex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Microneedle-Mediated Transdermal Delivery of Tizanidine Hydrochloride.
Tizanidine hydrochloride is a skeletal muscle relaxant used for the treatment of spasm, a sudden involuntary muscle contraction… 
2015
2015
Formulation and Evaluation of Mouth Dissolving Films Containing Tizanidine Hydrochloride
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2014
2014
Hot-melts in buccoadhesive patches: an approach for bioavailability enhancement of highly-metabolized drugs with short elimination half-life.
Highly Cited
2012
Highly Cited
2012
Improved transnasal transport and brain uptake of tizanidine HCl-loaded thiolated chitosan nanoparticles for alleviation of pain.
The aim of this study was to prepare and characterize thiolated chitosan (TC) nanoparticles (NPs) of tizanidine HCl (TZ) and to… 
2010
2010
Nightly Sublingual Tizanidine HCl in Multiple Sclerosis: Clinical Efficacy and Safety
Background:Approximately 90% of patients with multiple sclerosis (MS) experience spasticity during their lifetime. Tizanidine HCl… 
2009
2009
A combined approach of chemical enhancers and sonophoresis for the transdermal delivery of tizanidine hydrochloride.
The effects of chemical enhancers and sonophoresis on the transdermal permeation of tizanidine hydrochloride (TIZ) across mouse… 
2004
2004
Efficacy of tizanidine hydrochloride in the treatment of myofascial face pain.
AIM The aim of the present investigation was to evaluate the usefulness of tizanidine hydrochloride in the treatment of… 
2003
2003
Spectrophotometric Determination Of Tizanidine Hydrochloride
A new, simple, sensitive spectrophotometric method in ultraviolet region has been developed for the determination of tizanidine… 
2001
2001
Systemic Tizanidine Hydrochloride (Zanaflex™) Relieves Thermal Hyperalgesia in Rats with an Experimental Mononeuropathy
We sought to determine whether tizanidine, an &agr;2-agonist, relieved thermal hyperalgesia in rats with surgically induced… 
2001
2001
Systemic Tizanidine Hydrochloride (Zanaflex™) Partially Decreases Experimental Postoperative Pain in Rats
IMPLICATIONS Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained… 
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