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A study of rivastigmine liposomes for delivery into the brain through intranasal route
A study of rivastigmine liposomes for delivery into the brain through intranasal route The present study is mainly aimed at delivering a drug into the brain via the intranasal route using a liposomalExpand
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Glibenclamide transdermal patches: physicochemical, pharmacodynamic, and pharmacokinetic evaluations.
In the present study, matrix type transdermal patches containing glibenclamide were prepared using different ratios of ethyl cellulose (EC)/polyvinylpyrrolidone (PVP) and Eudragit RL-100Expand
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Solid dispersions: a review.
Solid dispersions have attracted considerable interest as an efficient means of improving the dissolution rate and hence the bioavailability of a range of hydrophobic drugs. This article reviews theExpand
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Formulation of plumbagin loaded long circulating pegylated liposomes: in vivo evaluation in C57BL/6J mice bearing B16F1 melanoma
Context and Objective: Plumbagin (2-methyl, 5-hydroxy, 1, 4-naphthoquinone), an anticancer agent is encapsulated either as conventional or long circulating liposomal formulations to enhance itsExpand
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Effect of Dianex, a herbal formulation on experimentally induced diabetes mellitus
Dianex, a polyherbal formulation consisting of the aqueous extracts of Gymnema sylvestre, Eugenia jambolana, Momordica charantia Azadirachta indica, Cassia auriculata, Aegle marmelose, WithaniaExpand
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Formulation development, in vitro and in vivo evaluation of membrane controlled transdermal systems of glibenclamide.
  • S. Mutalik, N. Udupa
  • Medicine, Chemistry
  • Journal of pharmacy & pharmaceutical sciences : a…
  • 21 January 2005
PURPOSE The objective of the present study was to develop the membrane controlled transdermal systems of glibenclamide and to evaluate with respect o various in vitro and in vivo parameters. Expand
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Antitumor and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma in vivo.
The antitumor and radiosensitizing effects of withaferin A (WA), a steroidal lactone from Withania somnifera, was studied on Ehrlich ascites carcinoma in vivo. The acute LD50(14) for WA in Swiss miceExpand
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Informed consent: Issues and challenges
Informed consent is an ethical and legal requirement for research involving human participants. It is the process where a participant is informed about all aspects of the trial, which are importantExpand
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Enhanced oral absorption of saquinavir with Methyl-Beta-Cyclodextrin-Preparation and in vitro and in vivo evaluation.
Saquinavir (SQV) is a weak base compound, whose solubility is strongly influenced by pH variations. Thus, in the present work, we thought it worthy of interest to investigate in-depth the combinedExpand
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Investigation into the potential of iontophoresis facilitated delivery of ketorolac.
  • S. Tiwari, N. Udupa
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 9 July 2003
The potential for iontophoresis facilitated transdermal transport of ketorolac was investigated using rat skin. Studies of electrical, physicochemical and device-related factors acting on theExpand
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