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Evaluation of antiplaque activity of Azadirachta indica leaf extract gel--a 6-week clinical study.
TLDR
The results of the study suggested that the dental gel containing neem extract has significantly reduced the plaque index and bacterial count than that of the control group.
A study of rivastigmine liposomes for delivery into the brain through intranasal route
TLDR
Delivering rivastigmine liposomes through the intranasal route for the treatment of Alzheimer's disease might be a new approach to the management of this condition.
Informed consent: Issues and challenges
TLDR
The obligations of investigator, sponsor and Institutional Review Board to protect rights and welfare of human research subjects and ethical challenges faced by physicians in obtaining informed consent from subjects are highlighted.
Glibenclamide transdermal patches: physicochemical, pharmacodynamic, and pharmacokinetic evaluations.
TLDR
The transdermal patches containing glibenclamide prevented the severe hypoglycemia in the initial hours and could maintain almost steady-state concentration of drug within the pharmacologically effective range for prolonged period of time, according to the pharmacokinetic evaluation.
Solid dispersions: a review.
TLDR
The various preparation techniques for solid dispersion are reviewed, an in-depth rationale for limited commercialization of solid dispersions and recent revival is considered and some of the recent technology transfers are compiled.
Effect of Dianex, a herbal formulation on experimentally induced diabetes mellitus
Dianex, a polyherbal formulation consisting of the aqueous extracts of Gymnema sylvestre, Eugenia jambolana, Momordica charantia Azadirachta indica, Cassia auriculata, Aegle marmelose, Withania
Formulation development, in vitro and in vivo evaluation of membrane controlled transdermal systems of glibenclamide.
  • S. Mutalik, N. Udupa
  • Medicine, Chemistry
    Journal of pharmacy & pharmaceutical sciences : a…
  • 21 January 2005
TLDR
The present study shows that membrane controlled transdermal systems of glibenclamide exhibited better control of hyperglycemia and more effectively reversed the diabetes mellitus complications than oral glibanclamide administration in mice.
Antitumor and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma in vivo.
TLDR
The antitumor and radiosensitizing effects of withaferin A (WA), a steroidal lactone from Withania somnifera, was studied on Ehrlich ascites carcinoma in vivo to study increase in life span and tumor-free survival.
In Situ Forming Polymeric Drug Delivery Systems
TLDR
The in situ gel forming polymeric formulations offer several advantages like sustained and prolonged action in comparison to conventional drug delivery systems, which reduces the investment and manufacturing cost from a manufacturing point of view.
Biosynthesis of copper nanoparticles using copper-resistant Bacillus cereus, a soil isolate
Abstract Microorganisms are useful systems for the production of biocompatible metal nanoparticles. Copper, an essential element of life, has good therapeutic potential. However, copper lacks
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