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tipranavir

Known as: 3'-((1R)-1-((6R)-5,6-dihydro-4-hydroxy-2-oxo-6-phenethyl-6-propyl-2h-pyran-3-yl)propyl)-5-(trifluoromethyl)-2-pyridinesulfonanilide, tipranavir [Chemical/Ingredient] 
A non-peptidomimetic agent that inhibits both wild type and drug resistant forms of human immunodeficiency virus (HIV) protease.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
We performed a systematic review and meta‐analysis of randomized controlled trials (RCTs) to assess the overall efficacy of new… 
2007
2007
Concomitant HIV and hepatitis C virus (HCV) is a common yet complex coinfection. The present document is a practical guide for… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND Current protease inhibitors (PIs) are designed against HIV-1, and information on their performance against HIV-2… 
2006
2006
Fifty-five patients placed on tipranavir/ritonavir 500/200 mg twice a day (27 with enfuvirtide and 28 without) underwent… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Human immunodeficiency virus type 2 (HIV-2) contains numerous natural polymorphisms in its protease (PR) gene that are… 
Highly Cited
2004
Highly Cited
2004
Abstract Purpose: To characterize the steady-state pharmacokinetic combination of the nonpeptidic protease inhibitor tipranavir… 
2004
2004
Abstract:Tipranavir (TPV), a novel nonpeptidic protease inhibitor (NPPI), was administered to treatment-naive HIV-1–infected…