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tiospirone

Known as: tiaspirone 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

MJ 13859

Broader (1)

Spiro Compounds

Papers overview

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Highly Cited
2005
Highly Cited
2005
Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia.
Serotonin 5-HT1A receptors are promising targets in the management of schizophrenia but little information exists about affinity… 
2001
2001
Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT(1A) receptors expressed in HeLa cells.
Review
2000
Review
2000
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
Clozapine is the prototype atypical antipsychotic drug, producing little or no extrapyramidal side effects, while improving… 
1997
1997
Actions of serotonergic agents on hypothalamic-pituitary-adrenal axis activity in the rat.
Highly Cited
1995
Highly Cited
1995
D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs
The affinities of 13 atypical and 12 typical antipsychotic drugs for the cloned rat D4 dopamine receptor and the D4/D2 ratios… 
Highly Cited
1994
Highly Cited
1994
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5… 
Highly Cited
1994
Highly Cited
1994
Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity.
Clozapine and haloperidol produce different induction patterns of c-fos expression in the forebrain, with haloperidol increasing… 
1992
1992
Neuroendocrinological and neurochemical effects of sigma ligands
1991
1991
Synthesis and biological activity of the putative metabolites of the atypical antipsychotic agent tiospirone.
Putative oxidative metabolites of the lead antipsychotic agent tiospirone (1) were synthesized to assist in the identification of… 
1991
1991
Metabolism of the antipsychotic drug tiospirone in humans.
Metabolism of the antipsychotic drug tiospirone was studied in humans after a single 60-mg oral dose of [14C]tiospirone… 
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