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Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons.
Prolonged treatment with classical antipsychotic drugs decreased the number of spontaneously active dopamine neurons in both the substantia nigra (A9) and the ventral tegmental area (A10) of the ratExpand
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Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro.
The effects of the antipsychotic drugs haloperidol and clozapine on N-methyl-D-aspartate (NMDA) and non-NMDA receptor-mediated neurotransmission were examined and compared in pyramidal cells of theExpand
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Pharmacological characterization of dopamine autoreceptors in the rat ventral tegmental area: microiontophoretic studies.
  • F. White, R. Y. Wang
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1 November 1984
Extracellular single-cell recording and microiontophoretic techniques were used to characterize the presynaptic dopamine (DA) receptors (autoreceptors) on A10 DA neurons in the rat ventral tegmentalExpand
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Physiological evidence for habenula as major link between forebrain and midbrain raphe.
The lateral habenula is one of the few forebrain areas that project to the midbrain raphe nuclei. Electrical stimulation of the habenula markedly suppressed serotonergic neurons in the midbrainExpand
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A10 dopamine neurons: role of autoreceptors in determining firing rate and sensitivity to dopamine agonists.
The present experiments investigated the relationship between the spontaneous basal firing rate of A10 dopamine (DA) neurons and their sensitivity to the rate-suppressant effects of intravenouslyExpand
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Electrophysiological characterization of 5-hydroxytryptamine2 receptors in the rat medial prefrontal cortex.
The aim of the present study was to characterize 5-hydroxytryptamine2 (5-HT2) receptors in the rat medial prefrontal cortex (mPFc) by single cell recording and microiontophoretic techniques. This wasExpand
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Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat.
The effects of chronic haloperidol (CHAL) treatment on A9 and A10 dopamine (DA) neurons were compared using extracellular single cell recording techniques. CHAL caused a time-dependent reduction inExpand
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Syndromic ear anomalies and renal ultrasounds.
OBJECTIVE Although many pediatricians pursue renal ultrasonography when patients are noted to have external ear malformations, there is much confusion over which specific ear malformations do and doExpand
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A pre‐ and postsynaptic modulatory action of 5‐HT and the 5‐HT2A, 2C receptor agonist DOB on NMDA‐evoked responses in the rat medial prefrontal cortex
Intracellular recordings were made from pyramidal neurons in layers V and VI of the rat medial prefrontal cortex in slice preparations to investigate the effect of the serotonin 5‐HT2A,2C receptorExpand
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Correlative firing patterns of serotonergic neurons in rat dorsal raphe nucleus
In this study, local neuronal interactions in the midbrain dorsal raphe nucleus (DRN) were analyzed by the use of autocorrelation and cross- correlation histograms. The autocorrelograms of serotoninExpand
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