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tiopronin

Known as: Thiopronine, Tiopronine, 2-Mercaptopropionylglycine 
An acylated sulfhydryl-containing derivative of glycine with reducing and complexing properties. Tiopronin breaks the disulphide bond of cystine and… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

AcadioneMeprinS-methylthiolaThiola
In BloodN-substituted Glycinesagonistsanalogs & derivatives

Broader (1)

Sulfhydryl Compounds

Papers overview

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Highly Cited
2001
Highly Cited
2001
Mitochondrial K(ATP) channel opening protects a human atrial-derived cell line by a mechanism involving free radical generation.
Highly Cited
1989
Highly Cited
1989
Fluorogenic reagent for thiols: 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole.
4-(N,N-Dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole (DBD-F) was synthesised for use as a more reactive, thiol-specific… 
1988
1988
Use of 4-(6-methylnaphthalen-2-yl)-4-oxobut-2-enoic acid as a reagent for the spectrophotometric and fluorimetric determination of aliphatic thiol drugs.
The aroylacrylic acid 4-(6-methylnaphthalen-2-yl)-4-oxobut-2-enoic acid is proposed as a useful reagent for the… 
1983
1983
Mechanism of the protective action of thiol compounds in ethanol-induced liver injury.
Highly Cited
1982
Highly Cited
1982
The reaction of the hydroxyl radical with glutathione in neutral and alkaline aqueous solution.
SJOBERG, L., ERIKSEN, T. E., AND REVESZ, L. The Reaction of the Hydroxyl Radical with Glutathione in Neutral and Alkaline Aqueous… 
Highly Cited
1981
Highly Cited
1981
Induction and repair of single-strand DNA breaks after X-irradiation of human fibroblasts deficient in glutathione.
Using the unwinding technique in weak alkali, the induction and repair of DNA single-strand breaks was determined after aerobic… 
Highly Cited
1978
Highly Cited
1978
Ethanol‐induced hepatotoxicity; experimental observations on the role of lipid peroxidation
Hepatic lipid peroxidation in vivo or in vitro as measured by UV absorption spectra of microsomal lipids or by production of TBA… 
Highly Cited
1977
Highly Cited
1977
Mercaptopropionylglycine: a progress in cystine stone therapy.
1972
1972
Radiation protection by 2-mercaptopropionylglycine in mice.
A new sulfhydryl compound, 2-mercaptopropionylglycine, which is commercially available in Japan as a detoxicating agent, has been… 
1968
1968
Treatment of cystinuria with alpha-mercaptopropionylglycine: a preliminary report with some notes on column chromatography of mercaptans.
  • J. King
  • Proceedings of the Society for Experimental…
  • 1968
  • Corpus ID: 44703728
SummaryIn acute trials α-mercaptopropionylglycine (MPG) appears to be approximately as effective as D-penicillamine in lowering… 
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