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tiopronin

Known as: Thiopronine, Tiopronine, 2-Mercaptopropionylglycine 
An acylated sulfhydryl-containing derivative of glycine with reducing and complexing properties. Tiopronin breaks the disulphide bond of cystine and… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

AcadioneMeprinS-methylthiolaThiola
In BloodN-substituted Glycinesagonistsanalogs & derivatives

Broader (1)

Sulfhydryl Compounds

Papers overview

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2005
2005
Inhibition of Qi site of mitochondrial complex III with antimycin A decreases persistent and transient sodium currents via reactive oxygen species and protein kinase C in rat hippocampal CA1 cells
2001
2001
In-vitro studies of aluminium-induced toxicity on kidney proximal tubular cells.
1999
1999
Tiopronin protects against the nephrotoxicity of cisplatin in the rat
1 Tiopronim (N-(2-mercaptopropionyl)-glycine) is a drug with a free thiol (sulphydryl) group that is used clinically. We have… 
Highly Cited
1989
Highly Cited
1989
Fluorogenic reagent for thiols: 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole.
4-(N,N-Dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole (DBD-F) was synthesised for use as a more reactive, thiol-specific… 
Review
1989
Review
1989
The Nephrotoxic Potential of Drugs and Chemicals Pharmacological Basis and Clinical Relevance
SummaryScores of drugs in common clinical use are capable of inflicting various degrees of damage to the kidney. Similarly, a… 
1988
1988
Use of 4-(6-methylnaphthalen-2-yl)-4-oxobut-2-enoic acid as a reagent for the spectrophotometric and fluorimetric determination of aliphatic thiol drugs.
The aroylacrylic acid 4-(6-methylnaphthalen-2-yl)-4-oxobut-2-enoic acid is proposed as a useful reagent for the… 
1988
1988
In vitro acantholysis by captopril and thiopronine.
The possible acantholytic property of captopril and thiopronine has been investigated using in vitro tissue cultures. Normal… 
1987
1987
High-performance liquid chromatography of 2-mercaptopropionylglycine and its metabolite 2-mercaptopropionic acid in plasma and urine after treatment with thiopronine.
Highly Cited
1981
Highly Cited
1981
Induction and repair of single-strand DNA breaks after X-irradiation of human fibroblasts deficient in glutathione.
Using the unwinding technique in weak alkali, the induction and repair of DNA single-strand breaks was determined after aerobic… 
Highly Cited
1978
Highly Cited
1978
Ethanol‐induced hepatotoxicity; experimental observations on the role of lipid peroxidation
Hepatic lipid peroxidation in vivo or in vitro as measured by UV absorption spectra of microsomal lipids or by production of TBA… 
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