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Meprin

 
National Institutes of Health

Papers overview

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2016
2016
BackgroundThe metalloprotease meprin β cleaves the Alzheimer’s Disease (AD) relevant amyloid precursor protein (APP) as a… Expand
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Highly Cited
2014
Highly Cited
2014
The mucus that covers and protects the epithelium of the intestine is built around its major structural component, the gel… Expand
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Review
2013
Review
2013
The metalloproteases meprin α and meprin β exhibit structural and functional features that are unique among all extracellular… Expand
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2013
2013
Type I fibrillar collagen is the most abundant protein in the human body, crucial for the formation and strength of bones, skin… Expand
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2012
2012
The amyloid β (Aβ) peptide, which is abundantly found in the brains of patients suffering from Alzheimer disease, is central in… Expand
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2011
2011
Identification of physiologically relevant substrates is still the most challenging part in protease research for understanding… Expand
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Highly Cited
2008
Highly Cited
2008
Interleukin-18 (IL-18), a pro-inflammatory cytokine, is a key factor in inflammatory bowel disease (IBD). Caspase-1 activates… Expand
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2007
2007
The zinc endopeptidase meprin (EC 3.4.24.18) is expressed in brush border membranes of intestine and kidney tubules, intestinal… Expand
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Highly Cited
2003
Highly Cited
2003
Meprin A and B, metalloproteases consisting of evolutionarily related alpha and/or beta subunits, are membrane-bound and secreted… Expand
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1994
1994
We have purified to homogeneity the enzyme in the kidney cortex which accounts for the vast majority of matrix-degrading activity… Expand
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