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thiopurine S-methyltransferase activity

Known as: mercaptopurine methyltransferase activity, TPMT, thiopurine methyltransferase activity 
Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. [EC:2.1.1.67]
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
In this contribution, the great potential of surface enhanced Raman spectroscopy (SERS) in a lab-on-a-chip (LOC) device for the… 
Review
2010
Review
2010
OBJECTIVES To examine whether pretreatment determination of thiopurine methyltransferase (TPMT) enzymatic activity (phenotyping… 
2001
2001
Azathioprine (AZA) is characterized by a high interindividual variability in bioavailability and metabolism. AZA is converted… 
2000
2000
Azathioprine is a purine analogue used as an immunosuppressive and immunomodulator agent in various mammals, including cats… 
1996
1996
Objective: Long-term (13 weeks) and circadian (24 hours) intraindividual variability in red blood cell (RBC) thiopurine… 
1995
1995
Thiopurine methyltransferase (TPMT), one of the enzymes involved in azathioprine metabolism, exhibits a wide range of activity in… 
1995
1995
Azathioprine is an immunosuppressor used with ciclosporin and corticosteroids after organ transplantation. Azathioprine is…