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thienamycin

Known as: 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-aminoethyl)thio)-6-(1-hydroxyethyl)-7-oxo-,, tienamycin 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Anti-Bacterial AgentsThienamycins
epithienamycin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Evidence that Thienamycin Biosynthesis Proceeds via C‐5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)‐trans‐Carboxymethylproline
The biosynthetic pathways leading to most clinically important families of bicyclic b-lactam antibiotics and b-lactamase… 
2008
2008
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis
The enzymatic activities of three proteins encoded by the thienamycin gene cluster of Streptomyces cattleya (ThnR, ThnH, and ThnT… 
1999
1999
Possible role of Chaetomium globosum in infection after autologous bone marrow transplantation
Sir: Immunocompromised patients develop severe fungal infections. Infections caused by opportunistic fungi such as Candida spp… 
1999
1999
Intramolecular N–H insertion of α-diazocarbonyls catalyzed by Cu(acac)2: An efficient route to derivatives of 3-oxoazetidines, 3-oxopyrrolidines and 3-oxopiperidines
Cu(acac)2 was found to be an efficient catalyst for the intramolecular N–H insertion by carbenoids. The competitive… 
1983
1983
Thienamycin production by immobilized cells of Streptomyces cattleya in a bubble column
A novel 2.0‐L columnar reactor has been developed for the production of thienamycin by cells of Streptomyces cattleya attached to… 
1982
1982
Comparative In Vitro Activities of N-Formimidoyl Thienamycin and Moxalactam Against Nonfermentative Aerobic Gram-Negative Rods
N-Formimidoyl thienamycin was the most active drug against strains of Pseudomonas aeruginosa with a 90% minimum inhibitory… 
1982
1982
In vitro activity and beta-lactamase stability of N-formimidoyl thienamycin compared to that of second and third generation cephalosporins.
N-Formimidoyl thienamycin (MK0787) was found to be active against 21 gram-negative isolates, selected for their beta-lactamase… 
1981
1981
In vitro activity of N-formimidoyl thienamycin (MK0787) against resistant strains of Pseudomonas aeruginosa, Staphylococcus epidermidis, Serratia marcescens, and Enterococcus spp
The in vitro activities of N-formimidoyl thienamycin (MK0787) and nine other antibiotics were tested against 129 clinical… 
1981
1981
Mutants of Streptomyces cattleya producing N-acetyl and deshydroxy carbapenems related to thienamycin.
Streptomyces cattleya NRRL 8057 produces the jl-lactam antibiotic thienamycin (1a) and traces of N-acetylthienamycin (lb)1). A… 
1981
1981
Epithienamycins-novel beta-lactams related to thienamycin. I. Production and antibacterial activity.
The epithienamycins are cell wall active antibiotics structurally related to N-acetylthienamycin. We have found forty-three… 
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