thienamycin

Known as: 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-aminoethyl)thio)-6-(1-hydroxyethyl)-7-oxo-,, tienamycin 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Despite their broad anti-infective utility, the biosynthesis of the paradigm carbapenem antibiotic, thienamycin, remains largely… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
Two regulatory genes, thnI and thnU, were identified in the thienamycin (thn) gene cluster from Streptomyces cattleya. ThnI… (More)
Is this relevant?
Review
1985
Review
1985
Imipenem (N-formimidoyl thienamycin) is the first representative of a new class of beta-lactam antibiotics--the carbapenems… (More)
Is this relevant?
Review
1983
Review
1983
Thienamycin, a natural product produced by Streptomyces cattleya is the first representative of a unique class of beta-lactam… (More)
Is this relevant?
1983
1983
The pharmacokinetics of intravenously administered N-formimidoyl thienamycin (MK0787) were studied in 14 healthy male subjects in… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Thienamycin (THM), the N-formimidoyl thienamycin derivative MK0787, and related carbapenem antibiotics were metabolized… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
1980
1980
The in vitro activity of a new crystalline derivative of thienamycin, N-formimidoyl thienamycin (MK0787), was tested against 46… (More)
  • table 1
  • table 1
  • table 3
Is this relevant?
1980
1980
The in vitro activity of N-formimidoyl thienamycin (MK0787), a stable congener of thienamycin, was determined against 200 species… (More)
  • table 1
Is this relevant?
1978
1978
The in vitro activity of thienamycin was tested against 135 aerobic and anaerobic bacteria. The compound was highly active… (More)
  • table 1
Is this relevant?
1977
1977
Thienamycin and clavulanic acid are new beta-lactam derivatives with structures markedly different from those of penicillins or… (More)
  • figure 2
  • figure 3
  • figure 1
  • figure 4
  • figure 5
Is this relevant?