Skip to search formSkip to main contentSkip to account menu

tetramethylpyrazine

Known as: TMPZ, chuanxiongzine, ligustrazine 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (3)

Liqustrazinetetramethyl pyrazinetetramethylpyrazine hydrochloride

Broader (2)

PyrazinesVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Tetramethylpyrazine nitrone activates the BDNF/Akt/CREB pathway to promote post‐ischaemic neuroregeneration and recovery of neurological functions in rats
Neuronal regeneration from endogenous precursors is an attractive strategy for the treatment of ischaemic stroke. However, most… 
Review
2016
Review
2016
Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has been extensively used in China for… 
Review
2016
Review
2016
Cardiovascular Actions and Therapeutic Potential of Tetramethylpyrazine (Active Component Isolated from Rhizoma Chuanxiong): Roles and Mechanisms
Tetramethylpyrazine (TMP), a pharmacologically active component isolated from the rhizome of the Chinese herb Rhizoma Chuanxiong… 
Highly Cited
2014
Highly Cited
2014
Neuroprotective Effects of Tetramethylpyrazine against Dopaminergic Neuron Injury in a Rat Model of Parkinson's Disease Induced by MPTP
Parkinson's disease (PD) is the second most prevalent progressive neurodegenerative disease. Although several hypotheses have… 
Highly Cited
2014
Highly Cited
2014
Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell…
Although kidney is a target organ of arsenic cytotoxicity, the underlying mechanisms of arsenic-induced nephrotoxicity remain… 
Highly Cited
2011
Highly Cited
2011
The protective mechanism of ligustrazine against renal ischemia/reperfusion injury.
Highly Cited
2010
Highly Cited
2010
High-yield fermentative preparation of tetramethylpyrazine by Bacillus sp. using an endogenous precursor approach
A spore-forming Bacillus sp. was isolated from a high-temperature Daqu, a starter culture of Chinese Maotai-flavor liquor, using… 
Highly Cited
2004
Highly Cited
2004
Effect of ligustrazine on ischemia-reperfusion injury in murine kidney.
Review
1993
Review
1993
Recent cardiovascular drugs from Chinese medicinal plants.
This paper describes the pharmacology of some recent cardiovascular drugs derived from plants used in Chinese traditional… 
Highly Cited
1992
Highly Cited
1992
Antiinflammatory effect of tetramethylpyrazine and ferulic acid.
Tetramethylpyrazine (TMP) is one of the alkaloids contained in Ligusticum wallichii Franch (L. wallichii). Ferulic acid (FA) is a… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)