tetrahydroquinoline

 
National Institutes of Health

Papers overview

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2014
2014
Antithrombotic agents that are inhibitors of factor XIa (FXIa) have the potential to demonstrate robust efficacy with a low… (More)
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2014
2014
Through their function as epigenetic readers of the histone code, the BET family of bromodomain-containing proteins regulate… (More)
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2012
2012
The cAMP-binding protein Epac is a therapeutic target for the treatment of various diseases such as cardiac hypertrophy and tumor… (More)
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2009
2009
A series of tetrahydroquinoline-derived inhibitors of the CRTH2 receptor was discovered by a high throughput screen. Optimization… (More)
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2007
2007
New antimalarials are urgently needed. We have shown that tetrahydroquinoline (THQ) protein farnesyltransferase (PFT) inhibitors… (More)
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2007
2007
The development of a novel series of tetrahydroquinoline-derived gamma-secretase inhibitors for the potential treatment of… (More)
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2007
2007
Substituted tetrahydroquinolines (THQs) have been previously identified as inhibitors of mammalian protein farnesyltransferase… (More)
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2004
2004
The ethyl acetate extract of cultures of Janibacter limosus showed a high biological activity against bacteria, and fungi and… (More)
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2002
2002
The antimalarial and toxicological properties of four tetrahydroquinoline alkaloids from Galipea officinalis trunk bark were… (More)
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Highly Cited
1995
Highly Cited
1995
The pharmacological properties of two recombinant human N-methyl-D-aspartate (NMDA) receptor subtypes, comprising either NR1a… (More)
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