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tenofovir alafenamide

Known as: TAF, bis{9-[(2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5?5-phosphaundecan-1-yl]-9H-purin-6-aminium} (2E)-but-2-enedioate, bis{propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate} (2E)-but-2-enedioate 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

GS-7340

Narrower (2)

Genvoyatenofovir alafenamide fumarate
emtricitabine / tenofovir alafenamide

Papers overview

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Highly Cited
2017
Highly Cited
2017
Brief Report: Randomized, Double-Blind Comparison of Tenofovir Alafenamide (TAF) vs Tenofovir Disoproxil Fumarate (TDF), Each Coformulated With Elvitegravir, Cobicistat, and Emtricitabine (E/C/F) for…
Abstract: In 2 double-blind phase 3 trials, 1733 antiretroviral-naive adults were randomized to tenofovir alafenamide (TAF) or… 
Highly Cited
2015
Highly Cited
2015
Implications of Efficient Hepatic Delivery by Tenofovir Alafenamide (GS-7340) for Hepatitis B Virus Therapy
ABSTRACT Tenofovir alafenamide (TAF) is a prodrug of tenofovir (TFV) currently in clinical evaluation for treatment for HIV and… 
Highly Cited
2007
Highly Cited
2007
Face Recognition Using Total Margin-Based Adaptive Fuzzy Support Vector Machines
This paper presents a new classifier called total margin-based adaptive fuzzy support vector machines (TAF-SVM) that deals with… 
Highly Cited
2004
Highly Cited
2004
Molecular architecture of the S. cerevisiae SAGA complex.
Highly Cited
2002
Highly Cited
2002
Proteomics of the Eukaryotic Transcription Machinery: Identification of Proteins Associated with Components of Yeast TFIID by Multidimensional Mass Spectrometry
ABSTRACT The general transcription factor TFIID is a multisubunit complex of TATA-binding protein (TBP) and 14 distinct TBP… 
Highly Cited
2002
Highly Cited
2002
New Degenerate Cytophaga-Flexibacter-Bacteroides-Specific 16S Ribosomal DNA-Targeted Oligonucleotide Probes Reveal High Bacterial Diversity in River Taff Epilithon
ABSTRACT River microbial communities play an important role in global nutrient cycles, and aggregated bacteria such as those in… 
Highly Cited
1995
Highly Cited
1995
Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II
Highly Cited
1994
Highly Cited
1994
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
Highly Cited
1994
Highly Cited
1994
Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA.
In Drosophila and human cells, the TATA binding protein (TBP) of the transcription factor IID (TFIID) complex is tightly… 
Highly Cited
1993
Highly Cited
1993
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators
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