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tenofovir alafenamide

Known as: TAF, bis{9-[(2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5?5-phosphaundecan-1-yl]-9H-purin-6-aminium} (2E)-but-2-enedioate, bis{propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate} (2E)-but-2-enedioate 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

GS-7340

Narrower (2)

Genvoyatenofovir alafenamide fumarate
emtricitabine / tenofovir alafenamide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Fanconi Syndrome and Tenofovir Alafenamide
TO THE EDITOR: Some issues in Bahr and colleagues' (1) case report on a patient with Fanconi syndrome caused by tenofovir… 
2012
2012
Direct Observation of Protein Microcrystals in Crystallization Buffer by Atmospheric Scanning Electron Microscopy
X-ray crystallography requires high quality crystals above a given size. This requirement not only limits the proteins to be… 
Highly Cited
1999
Highly Cited
1999
The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2.
Transcriptional activation domains share little sequence homology and generally lack folded structures in the absence of their… 
1999
1999
Cell cycle-dependent regulation of RNA polymerase I transcription : The nucleolar transcription factor UBF is inactive in mitosis and early G 1
Transcription of ribosomal RNA genes by RNA polymerase (pol) I oscillates during the cell cycle, being maximal in S and G2 phase… 
Highly Cited
1998
Highly Cited
1998
Mitotic phosphorylation of the TBP-containing factor SL1 represses ribosomal gene transcription.
Entry into mitosis is accompanied by a global repression of transcription. To investigate the molecular mechanisms which shut… 
1998
1998
Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein.
Phorbol ester treatment of U937 leukemic cells results in the activation of numerous protein kinase pathways, followed by cell… 
1997
1997
Cloning and Characterization of an Essential Saccharomyces cerevisiae Gene, TAF40, Which Encodes yTAFII40, an RNA Polymerase II-specific TATA-binding Protein-associated Factor*
In this report we describe the cloning and initial characterization of TAF40, a gene that encodes a yeast TATA-binding protein… 
1996
1996
Crystal and Molecular Structure of the [6-Deoxy-6-[(2-(4-imidazolyl)ethyl)amino]- cyclomaltoheptaose]copper(II) Ternary Complex with L-Tryptophanate. Role of Weak Forces in the Chiral Recognition…
The ternary copper(II) complex of 6-deoxy-6-[(2-(4-imidazolyl)ethyl)amino]cyclomaltoheptaose (CDhm) and L-tryptophanate (L-TrpO… 
1994
1994
Protein/DNA crosslinking of a TFIID complex reveals novel interactions downstream of the transcription start.
A protein--DNA complex containing TFIID has been analyzed by crosslinking. The TBP subunit of TFIID crosslinked to the TATA… 
1993
1993
Functional domains of the simian foamy virus type 1 transcriptional transactivator (Taf)
The genome of simian foamy virus type 1 encodes a transcriptional transactivator (Taf) that dramatically elevates gene expression… 
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