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tenidap

Known as: 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Anti-Inflammatory Agents, Non-SteroidalCyclooxygenase InhibitorsIndoles

Narrower (1)

tenidap sodium

Papers overview

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Highly Cited
2003
Highly Cited
2003
Evaluation of the Ocular Hypotensive Response of Serotonin 5-HT1A and 5-HT2 Receptor Ligands in Conscious Ocular Hypertensive Cynomolgus Monkeys
Published investigations of serotonin-1A (5-hydroxytryptamine1A; 5-HT1A) receptor agonists and serotonin-2A (5… 
2001
2001
The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: inhibition by tenidap and benzamil and effect of temperature on transport rate and stoichiometry
Abstract. In the present experiments we expressed the rat kidney Na+-HCO3– cotransporter (rkNBC) in Xenopus laevis oocytes to… 
2000
2000
Effects of the second-generation leukotriene B(4) receptor antagonist, LY293111Na, on leukocyte infiltration and collagen-induced arthritis in mice.
Highly Cited
1998
Highly Cited
1998
Analysis of changes in acute‐phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two‐dimensional gel electrophoresis
Two‐dimensional (2‐D) gel analysis was used to examine differences in the levels of 19 plasma proteins: before and after an acute… 
Highly Cited
1996
Highly Cited
1996
Meloxicam: influence on arachidonic acid metabolism. Part II. In vivo findings.
Highly Cited
1995
Highly Cited
1995
Endothelium-dependent contractions are associated with both augmented expression of prostaglandin H synthase-1 and hypersensitivity to prostaglandin H2 in the SHR aorta.
Prostaglandin H2 (PGH2 [endoperoxide]) is an immediate product of prostaglandin H (PGH) synthase activity (cyclooxygenase) and a… 
Highly Cited
1995
Highly Cited
1995
Effects of tenidap on canine experimental osteoarthritis. I. Morphologic and metalloprotease analysis.
OBJECTIVE To examine the effects of tenidap and diclofenac on osteoarthritic lesions and metalloprotease activity in experimental… 
Highly Cited
1994
Highly Cited
1994
Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. II. Inhibition of IL-1 beta production from ATP-treated monocytes and macrophages.
IL-1 beta is an important inflammatory mediator produced by monocytes and macrophages after LPS stimulation. In the absence of a… 
Highly Cited
1992
Highly Cited
1992
Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response.
The cytokines IL-6, IL-1, and TNF play a key role in the pathogenesis of rheumatoid arthritis (RA) and initiate hepatic serum… 
Highly Cited
1992
Highly Cited
1992
A calcium and ATP sensitive nonselective cation channel in the antiluminal membrane of rat cerebral capillary endothelial cells.
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