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temoporfin

Known as: meso-tetrahydroxyphenylchlorin, m-THPC, meta-Tetrahydroxyphenyl Chlorin 
A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic AgentsMesoporphyrinsPhotosensitizing AgentsRadiation-Sensitizing Agents

Narrower (2)

FoscanFoslip
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Self-assemblies of meso-tetraphenylporphine ligand on surfaces of highly oriented pyrolytic graphite and single-walled carbon nanotubes: insights from scanning tunneling microscopy and molecular…
The self-assembly of porphyrins into highly organized functional arrays supported on appropriate solid substrates is an area of… 
Highly Cited
2008
Highly Cited
2008
Formation of efficient dye-sensitized solar cells by introducing an interfacial layer of long-range ordered mesoporous TiO2 thin film.
Long-range ordered cubic mesoporous TiO 2 films with 300 nm thickness were fabricated on fluorine-doped tin oxide (FTO) substrate… 
Highly Cited
2006
Highly Cited
2006
Spectroscopic determination of proton position in the proton-coupled electron transfer pathways of donor-acceptor supramolecule assemblies.
A homologous set of porphyrin derivatives possessing an isocyclic five-membered ring appended with an amidinium functionality has… 
Highly Cited
2003
Highly Cited
2003
Efficient excitation energy transfer in long meso-meso linked Zn(II) porphyrin arrays bearing a 5,15-bisphenylethynylated Zn(II) porphyrin acceptor.
Electronically coupled porphyrin arrays are suitable for artificial light harvesting antenna in light of a large absorption cross… 
Highly Cited
2002
Highly Cited
2002
In Vivo mTHPC Photobleaching in Normal Rat Skin Exhibits Unique Irradiance-dependent Features¶
Abstract We report measurements performed on the normal skin of rats in vivo, which provide information on the photobleaching… 
Highly Cited
2001
Highly Cited
2001
Targeting of aluminum (III) phthalocyanine tetrasulfonate by use of internalizing monoclonal antibodies: improved efficacy in photodynamic therapy.
The use of monoclonal antibodies (MAbs) directed against tumor-associated antigens for targeting of photosensitizers is an… 
Highly Cited
1999
Highly Cited
1999
A Comparative Study of the Cellular Uptake and Photodynamic Efficacy of Three Novel Zinc Phthalocyanines of Differing Charge
Abstract— Three novel substituted zinc (II) phthalocyanines (one anionic, one cationic and one neutral) were compared to two… 
Highly Cited
1998
Highly Cited
1998
Photodynamic therapy for gastrointestinal tumors using three photosensitizers--ALA induced PPIX, Photofrin and MTHPC. A pilot study.
Photodynamic therapy (PDT) produces localized necrosis with light after prior administration of a photosensitizing drug. As PDT… 
Highly Cited
1995
Highly Cited
1995
Uptake, localization, and photodynamic effect of meso-tetra(hydroxyphenyl)porphine and its corresponding chlorin in normal and tumor tissues of mice bearing mammary carcinoma.
By using a chemical extraction assay and confocal laser scanning fluorescence microscopy, the kinetic patterns of uptake… 
Highly Cited
1993
Highly Cited
1993
Effect of drug‐light interval on photodynamic therapy with meta‐tetrahydroxyphenylchlorin in malignant mesothelioma
The influence of the time interval (TI) between drug administration and laser activation on selectivity of meta‐tetrahydroxy… 
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