telocinobufagin

Known as: 3,5,14-trihydroxybufa-20,22-dienolide 
 
National Institutes of Health

Papers overview

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2016
2016
[Mechanism of colon cancer cell apoptosis induced by telocinobufagin: role of oxidative stress and apoptosis pathway].
OBJECTIVE To investigate the effects of telocinobufagin on viability and apoptosis of colorectal cancer (CRC) cells and explore… (More)
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2016
2016
Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cells.
The growth inhibitory effects of bufadienolide compounds were investigated in two intractable cancer cells, a human glioblastoma… (More)
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2015
2015
Telocinobufagin enhances the Th1 immune response and protects against Salmonella typhimurium infection.
Ideal potential vaccine adjuvants to stimulate a Th1 immune response are urgently needed to control intracellular infections in… (More)
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2012
2012
Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.
Venenum Bufonis, a traditional Chinese medicine, is widely used in the treatment of liver cancer in modern Chinese medical… (More)
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2011
2011
Biotransformation of bufadienolides by cell suspension cultures of Saussurea involucrata.
The biotransformation of three bioactive bufadienolides, namely, bufotalin (1), telocinobufagin (2), and gamabufotalin (3) by… (More)
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2011
2011
Inhibitory effect of combinations of digoxin and endogenous cardiotonic steroids on Na+/K+-ATPase activity in human kidney membrane preparation.
AIMS Cardiac glycosides have been extensively used in the treatment of congestive heart failure for more than 200 years. Recently… (More)
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2010
2010
Cytotoxic profile of natural and some modified bufadienolides from toad Rhinella schneideri parotoid gland secretion.
Cutaneous secretions of toad species are an important source of bufadienolides, compounds that exhibit interesting structural… (More)
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2009
2009
The effects of telocinobufagin isolated from Chan Su on the activation and cytokine secretion of immunocytes in vitro.
Many traditional Chinese medicines have been used as immunomodulators that act as either immunosuppressants or immunostimulators… (More)
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2008
2008
Antileishmanial and antitrypanosomal activity of bufadienolides isolated from the toad Rhinella jimi parotoid macrogland secretion.
Amphibian skin secretions are considered a rich source of biologically active compounds and are known to be rich in peptides… (More)
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2005
2005
Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens.
The increase in the emergence of antibiotic-resistant microorganisms and difficult to treat infections caused by these pathogens… (More)
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