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- Publications
- Influence
Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium
AbstractMedical application of Panax ginseng was first found in “Shen-Nong Herbal Classic” around 200 AD Panax quinquefolium was first introduced in “Essential of Materia Medica” in 1694 in China.… Expand
Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti‐inflammatory effect
- Yuh-Chiang Shen, C. Chen, W. Chiou
- Chemistry, Medicine
- British journal of pharmacology
- 1 January 2002
We have reported that andrographolide (ANDRO), an active component of Andrographis paniculata, inhibits inflammatory responses by rat neutrophils. To further elucidate the possible mechanism(s)… Expand
The anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species production.
- K. Liou, Yuh-Chiang Shen, C. Chen, C. Tsao, S. Tsai
- Chemistry, Medicine
- European journal of pharmacology
- 15 August 2003
Reactive oxygen species produced by neutrophils contribute to the pathogenesis of focal cerebral ischemia/reperfusion injury and signal the inflammatory response. We have previously shown that… Expand
Antitumor Effects of Ganoderma Lucidum
- Shiuh-Sheng Lee, Y. Wei, C. Chen, Sheng-Yuan Wang, Kuang-Yao Chen
- Biology
- 1 March 1995
Ganoderma lucidum has been established to be an autitumor natural product. The hot water extracts of the mycelium of G. lucidum (GLP) exhibited antitumor effect against fibrosarcoma in male and… Expand
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Honokiol protects rat brain from focal cerebral ischemia–reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production
- K. Liou, Yuh-Chiang Shen, C. Chen, C. Tsao, S. Tsai
- Medicine
- Brain Research
- 5 December 2003
We have previously shown that honokiol, an active component of Magnolia officinalis, displayed protective effect against focal cerebral ischemia-reperfusion (FCI/R) injury in rats. Production of… Expand
Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties
- L. Zhang, Yiu-Keung Lau, +6 authors M. Hung
- Biology, Medicine
- Oncogene
- 4 June 1998
We have previously shown that emodin suppresses tyrosine kinase activity of HER-2/neu-encoded p185neu receptor tyrosine kinase. In this study, we examine the relationship between the chemical… Expand
Two novel sesquiterpene lactones, cytotoxic vernolide-A and -B, from Vernonia cinerea.
Bioassay-directed fractionation of an ethanolic extract of stems of Vernonia cinerea has resulted in the isolation of two novel sesquiterpene lactones, vernolide-A and -B. Their structures were… Expand
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes.
- Yuh-Chiang Shen, W. Chiou, Y. Chou, C. Chen
- Chemistry, Medicine
- European journal of pharmacology
- 28 March 2003
To evaluate the possible mechanisms responsible for the anti-inflammatory effects of baicalin or baicalein, phorbol-12-myristate-13-acetate (PMA)- or N-formyl-methionyl-leucyl-phenylalanine… Expand
Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata.
- Yuh-Chiang Shen, Yea-Hwey Wang, +5 authors Cheng-Jen Chou
- Medicine, Chemistry
- Planta medica
- 1 April 2004
We have previously shown that a concentrated ethanol extract of the fruiting bodies of Antrodia camphorata exhibited immunomodulating effects in human leukocytes and fourteen compounds including… Expand
Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes
- Y. Shiao, Y. Lin, Y. Sun, chih-Wen chi, C. Chen, Chuen-Neu Wang
- Biology, Medicine
- British journal of pharmacology
- 1 January 2005
1 The effects of falcarindiol on the expression of inducible nitric oxide synthase (iNOS) induced by lipopolysaccharide/interferon‐γ (LPS/IFN‐γ) in rat primary astrocytes were investigated. The… Expand