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telavancin

Known as: Telavancina, Telavancinum, (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-5,15-dichloro-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-{[2-(decylamino)ethyl]amino}-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2 
National Institutes of Health

Related topics

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7 relations

Broader (2)

AminoglycosidesAnti-Bacterial Agents
Bacterial InfectionsLipoglycopeptides [Chemical/Ingredient]telavancin 250 MG Injection [Vibativ]telavancin hydrochloride

Narrower (1)

TD 6424

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Population Pharmacokinetics of Telavancin in Healthy Subjects and Patients with Infections
ABSTRACT A population pharmacokinetic model of telavancin, a lipoglycopeptide antibiotic, was developed and used to identify… 
2012
2012
Vancomycin Tolerance in Methicillin-Resistant Staphylococcus aureus: Influence of Vancomycin, Daptomycin, and Telavancin on Differential Resistance Gene Expression
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) isolates that are susceptible to vancomycin but are tolerant to its… 
2010
2010
Fresh from the biologic pipeline—2009
Human antibodies take center stage, as they pile up in the list of approved biologics in 2009. Cormac Sheridan reports. 
2010
2010
Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia.
OBJECTIVES Infections caused by heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) are associated with high… 
Review
2009
Review
2009
Treatments for skin and soft-tissue and surgical site infections due to MDR Gram-positive bacteria.
2009
2009
Activity of Telavancin against Staphylococcus aureus Strains with Various Vancomycin Susceptibilities in an In Vitro Pharmacokinetic/Pharmacodynamic Model with Simulated Endocardial Vegetations
ABSTRACT We investigated the activity of telavancin, a novel lipoglycopeptide, alone and combined with gentamicin or rifampin… 
Highly Cited
2008
Highly Cited
2008
In vitro activity of telavancin against recent Gram-positive clinical isolates: results of the 2004-05 Prospective European Surveillance Initiative.
OBJECTIVES Telavancin is a novel semi-synthetic lipoglycopeptide currently in late-stage clinical development for the treatment… 
Review
2008
Review
2008
A new lipoglycopeptide: telavancin.
The increase in infections caused by resistant Gram-positive organisms has led to an urgent need for new antibiotics. Telavancin… 
2007
2007
Efficacy of Telavancin in the Treatment of Experimental Endocarditis Due to Glycopeptide-Intermediate Staphylococcus aureus
ABSTRACT The efficacy of telavancin, a novel lipoglycopeptide, was evaluated in experimental endocarditis in rabbits using two… 
2007
2007
Efficacy of telavancin in a murine model of pneumonia induced by methicillin-susceptible Staphylococcus aureus.
OBJECTIVES To assess the efficacy of telavancin, a rapidly bactericidal lipoglycopeptide, and three comparator agents in a murine… 
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