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tautomycin

 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Protein phosphatase 1 occurs in all tissues and regulates many pathways, ranging from cell-cycle progression to carbohydrate… Expand
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Highly Cited
2002
Highly Cited
2002
In adipocytes, protein kinase B (PKB) has been suggested to be the enzyme that phosphorylates phosphodiesterase 3B (PDE3B), a key… Expand
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Highly Cited
2001
Highly Cited
2001
BAD is a proapoptotic member of the BCL-2 family of proteins, which play a major role in regulating apoptosis in cytokine… Expand
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Highly Cited
1998
Highly Cited
1998
The role of Rho GTPase and its downstream targets Rho kinase and myosin light chain phosphatase in thrombin-induced endothelial… Expand
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Highly Cited
1997
Highly Cited
1997
Calyculin-A (CA), okadaic acid (OA), and tautomycin (TAU) are potent inhibitors of protein phosphatases 1 (PP1) and 2A (PP2A) and… Expand
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Highly Cited
1995
Highly Cited
1995
Human furin catalyzes the proteolytic maturation of many proproteins in the exocytic and endocytic secretory pathways by cleavage… Expand
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Highly Cited
1995
Highly Cited
1995
Several groups have reported that okadaic acid (OA) and some other tight-binding protein phosphatase inhibitors including… Expand
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Highly Cited
1994
Highly Cited
1994
Recent studies suggest that the ability to inhibit the activity of certain serine/threonine protein phosphatases underlies the… Expand
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Highly Cited
1992
Highly Cited
1992
We have used a combination of highly specific protein phosphatase inhibitors and purified mammalian protein phosphatases to show… Expand
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Highly Cited
1991
Highly Cited
1991
The antibiotic, tautomycin, was found to be a potent inhibitor of protein phosphatases and equally effective for the type‐1 and… Expand
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