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taurolidine

Known as: bis(1,1-dioxo-perhydro-1,2,4-thiadiazinyl-4)methane, Bis(1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)-methane, bis- (1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)methane 
A synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities. Taurolidine, derived from the amino… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (5)

Anti-Infective AgentsAnti-Infective Agents, LocalAntineoplastic AgentsTaurine
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Narrower (2)

TauroflexTaurolin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Synthesis of geminal bis- and tristriazoles: exploration of unconventional azide chemistry.
A range of geminal bis- and tristriazoles are presented. These rare and hardly studied compound classes were easily synthesized… 
2014
2014
Estudio de la eficacia del sellado con taurolidina y citrato 4% del catéter para hemodiálisis en la prevención de infección y trombosis
Resumen es: El uso de cateteres centrales ha aumentan- do de forma importante a pesar de su mayor morbi-mortalidad en comparacion… 
2012
2012
TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cells.
BACKGROUND Disseminated fibrosarcoma still represents a therapeutic dilemma because of lack of effective cytostatics. Therefore… 
2008
2008
Inhibition of endothelial cell adhesion and in vitro angiogenesis by Taurolidine
Summary Taurolidine is a clinically active tumor suppressing agent. To gather experimental evidence whether an antiangiogenic… 
1997
1997
Adjuvant therapy of peritonitis with taurolidine. Modulation of mediator liberation
Despite aggressive surgical treatment, prompt antibiotic therapy, and modern intensive care, up to one half of patients still die… 
1996
1996
Conformational analysis of (R,R)- and (R,S)-N,N-bis(1-phenylethyl)-acetamide and -thioacetamide. A study by NMR spectroscopy and by empirical force-field and AM1 calculations
The static and dynamic stereochemistry of the diastereoisomeric (R,S)- and (R,R)-N,N-bis(1-phenylethyl)acetamides and their thio… 
1994
1994
Beneficial effects of taurolidine in experimental pancreatitis.
Taurolidine has potent antiendotoxin and antimicrobial effects in vitro. This study assessed the effect of taurolidine in a well… 
1983
1983
Taurolidine instillation as therapy for empyema thoracis. A prospective study of 50 patients.
Fifty patients with chronic empyema thoracis, without bronchopleural fistula, were treated by drainage and twice-daily… 
1969
1969
全身オートラジオグラティによる放射性化合物の生体内分布に関する研究 (第19報):マウス, ラット, ニワトリにおける 35 S-bis- (3, 5-dichloro-2-hydroxyphenyl) sulfoxideの分布
マウス, ラットおよびニワトリにおける35S-bis- (3, 5-dichloro-2-hydroxypheny1) sulfoxide (35S-Bitin-S… 
1942
1942
Studies on the Anticoagulant 3,3 -Methylene-Bis- (4-Hydroxycoumarin)
Continents and Summary 3,3′-methyIene-bis-(4-hydroxycoumarin), Dicumarol, was shown in our experiments to be able to greatly… 
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