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taurochenodeoxycholate 6alpha-hydroxylase activity

Known as: CYP4A21, taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity, CYP3A4 
Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2… 
National Institutes of Health

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3 relations
Cytochrome P-450 CYP3A4cytochrome P450 3A4 protein, humantaurochenodeoxycholic acid 6-alpha-hydroxylase

Papers overview

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2007
2007
Identification and hepatic expression profiles of cytochrome P450 1-4 isozymes in common minke whales (Balaenoptera acutorostrata).
2004
2004
The porcine taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21) gene: evolution by gene duplication and gene conversion.
Porcine taurochenodeoxycholic acid 6alpha-hydroxylase, cytochrome P450 4A21 (CYP4A21), differs from other members of the CYP4A… 
2003
2003
Gene structure of pig sterol 12alpha-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21).
2003
2003
Porcine taurochenodeoxycholic acid 6α-hydroxylase (CYP4A21) : gene organisation and aspects on the evolution of the CYP4A subfamily
Porcine taurochenodeoxycholic acid 6α-hydroxylase (CYP4A21) : gene organisation and aspects on the evolution of the CYP4A… 
2002
2002
Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25].
A new member of the cytochrome P450 (CYP) 4A subfamily (CYP4A21) was recently cloned by PCR from pig liver [Lundell, Hansson, and… 
2001
2001
Cloning and expression of a pig liver taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21): a novel member of the CYP4A subfamily.
A cytochrome P450 expressed in pig liver was cloned by polymerase chain reaction using oligonucleotide primers based on amino… 
2001
2001
Cloning and Expression of a Pig Liver Taurochenodeoxycholic Acid 6 a-Hydroxylase ( CYP 4 A 21 )
A cytochrome P450 expressed in pig liver was cloned by polymerase chain reaction using oligonucleotide primers based on amino… 
1989
1989
Effects of monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids in hamsters.
1979
1979
Taurocholate uptake by adult rat hepatocytes in primary culture.
Adult rat hepatocytes were cultured on Petri dishes for 25--30 h prior to measuring their ability to transport taurocholate. A… 
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