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taprostene

Known as: 2,3,4-trinor-1,5-inter-2-phenylene-6,9-epoxy-11,15-dihydroxy-15-dihydroxy-15-cyclohexyl-(16,17,18,19,20-pentanor)prosta-5,13-dienoate, Benzoic acid, 3-((4-(3-cyclohexyl-3-hydroxy-1-propenyl)hexahydro-5-hydroxy-2H-cyclopenta(b)furan-2-ylidene)methyl)-, monosodium salt, (3aR-(2Z,3aalpha,4alpha(1E,3S*),5beta,6aalpha))- 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

CG 4203

Broader (2)

Cardiovascular AgentsEpoprostenol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Evidence for a Second Receptor for Prostacyclin on Human Airway Epithelial Cells That Mediates Inhibition of CXCL9 and CXCL10 Release
Herein we provide evidence for the coexpression of two distinct prostacyclin (PGI2) receptors (IP) on BEAS-2B human airway… 
2008
2008
4,5-Dihydro-1H-imidazol-2-yl)-[4-(4-isopropoxy-benzyl)-phenyl]-amine (RO1138452) Is a Selective, Pseudo-Irreversible Orthosteric Antagonist at the Prostacyclin (IP)-Receptor Expressed by Human Airway…
The extent to which the prostacyclin (IP) receptor regulates the release of two proinflammatory chemokines from human airway… 
2004
2004
Agonists can discriminate between cloned human and mouse prostacyclin receptors.
Review
1999
Review
1999
Use of prostacyclin and its analogues in the treatment of cardiovascular disease.
Prostacyclin is found in all body tissues and body fluids, and is the major metabolite of arachidonic acid in the vasculature. It… 
1994
1994
Expression of Adhesion Molecules on the Surface of Activated Platelets is Diminished by PGI(2)-analogues and an NO (EDRF)-Donor: A Comparison Between Platelets of Healthy and Diabetic Subjects.
Adhesion molecules such as P-selectin (CD 62), glycoprotein (CP) 53 (CD63) and thrombospondin play a decisive role in the… 
1993
1993
The effect of taprostene in patients with acute myocardial infarction treated with thrombolytic therapy: results of the STARTstudy
Taprostene is a prostacyclin analogue that inhibits platelet aggregation and thus might be a useful adjuvant to thrombolytic… 
1991
1991
Beneficial effects of the prostacyclin analogue taprostene on cardiovascular, pulmonary and renal disturbances in endotoxin-shocked rabbits.
The prostacyclin analogue taprostene protects against lethal endotoxemia in rats. In the present study, the effects of taprostene… 
1991
1991
Effects of prostacyclin and taprostene in splanchnic artery occlusion shock.
: Prostacyclin (PGI2) and taprostene (CG-4203) were studied in a highly lethal model of splanchnic artery occlusion (SAO) shock… 
1990
1990
In vitro studies with the stabilized epoprostenol analogue taprostene. Effect on platelets and erythrocytes.
In vitro, the oxacyclic epoprostenol (prostacyclin) analogue taprostene like the native epoprostenol inhibited platelet… 
1990
1990
In vivo studies with the stabilized epoprostenol analogue taprostene. Effects on platelet functions and blood clotting.
Like the native epoprostenol (prostacyclin, PGI2), the oxacyclic epoprostenol analogue taprostene affects platelet functions. In… 
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