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tapentadol

Known as: 3-((1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl)phenol 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (3)

BN-200NucyntaTapentadol hydrochloride
Opioid Agonists [MoA]Tapentadol glucuronide:MCnc:Pt:Urine:Qn:ScreenTapentadol/Creatinine:MRto:Pt:Urine:QnTapentadol:PrThr:Pt:Urine:Ord:Confirm

Broader (1)

Phenols

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tapentadol prolonged-release for moderate-to-severe chronic osteoarthritis knee pain: a double-blind, randomized, placebo- and oxycodone controlled release-controlled study
Abstract Objective: To assess efficacy and safety of tapentadol prolonged release (PR) for moderate-to-severe chronic… 
2017
2017
Effect of Tapentadol on Splenic Cytokine Production in Mice
BACKGROUND: Opioid drugs affect immunity, but not all opioid drugs share the same immunomodulatory properties. Tapentadol is an… 
2016
2016
Single-isomer carboxymethyl-γ-cyclodextrin as chiral resolving agent for capillary electrophoresis.
Highly Cited
2015
Highly Cited
2015
Effectiveness and Safety of Tapentadol Prolonged Release (PR) Versus a Combination of Tapentadol PR and Pregabalin for the Management of Severe, Chronic Low Back Pain With a Neuropathic Component: A…
To evaluate the effectiveness and tolerability of tapentadol PR monotherapy versus tapentadol PR/pregabalin combination therapy… 
Review
2015
Review
2015
Tapentadol Toxicity in Children
BACKGROUND: Tapentadol (Nucynta) is indicated for the treatment of moderate to severe pain in adults. Tapentadol’s mechanism of… 
2014
2014
The Noradrenergic Component in Tapentadol Action Counteracts μ-Opioid Receptor–Mediated Adverse Effects on Adult Neurogenesis
Opiates were the first drugs shown to negatively impact neurogenesis in the adult mammalian hippocampus. Literature data also… 
2014
2014
Chronic pain, addiction, and Zohydro.
Twenty-nine state attorneys general have asked the FDA to reconsider its approval of the opioid Zohydro, which lacks abuse… 
Review
2013
Review
2013
Tapentadol Extended Release for Chronic Pain Patients
IntroductionChronic pain reduces quality of life, utilizes healthcare resources, and increases healthcare costs. It is widespread… 
2013
2013
Tapentadol Prolonged Release for Severe Chronic Pain: Results of a Noninterventional Study Involving General Practitioners and Internists
ABSTRACT This noninterventional, prospective study investigated the administration of tapentadol prolonged release (PR; the… 
Review
2010
Review
2010
Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: tapentadol, a step toward a solution?
Abstract Objective: Opioids are among the most effective and potent analgesics currently available. Their utility in the… 
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