tapentadol

Known as: 3-((1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl)phenol 
 

Topic mentions per year

Topic mentions per year

2007-2017
020406020072017

Papers overview

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Painful diabetic peripheral neuropathy (DPN) may not be adequately managed with available therapeutic options. This… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To evaluate the efficacy and safety of tapentadol extended release (ER) for the management of moderate to severe… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Tapentadol is a novel, centrally acting analgesic with mu-opioid receptor agonist and norepinephrine reuptake… (More)
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2010
2010
Tapentadol is a novel, centrally acting analgesic combining micro-opioid receptor (MOR) agonism and noradrenaline (NA) reuptake… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Tapentadol is a novel, centrally acting analgesic with 2 mechanisms of action: µ-opioid receptor agonism and… (More)
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2010
2010
INTRODUCTION This pooled analysis of data from three phase 3 studies in patients with chronic osteoarthritis knee or low back… (More)
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2009
2009
OBJECTIVE To evaluate the relative efficacy and tolerability of tapentadol immediate release (IR) and oxycodone IR for management… (More)
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2007
2007
(-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl) is a novel micro-opioid receptor… (More)
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2007
2007
Tapentadol is a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical… (More)
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2007
2007
( )-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl) is a novel -opioid receptor (MOR… (More)
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