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tanshinone II A

Known as: tanshinone IIA 
National Institutes of Health

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tanshinone

Papers overview

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Highly Cited
2018
Highly Cited
2018
Rebuilding Postinfarcted Cardiac Functions by Injecting TIIA@PDA Nanoparticle-Cross-linked ROS-Sensitive Hydrogels.
Drug-loaded injectable hydrogels have been proven to possess huge potential for applications in tissue engineering. However… 
Highly Cited
2015
Highly Cited
2015
The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line
Highly Cited
2014
Highly Cited
2014
Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1[S]
Accumulation of foam cells in the neointima represents a key event in atherosclerosis. We previously demonstrated that Tanshinone… 
Highly Cited
2014
Highly Cited
2014
Tanshinone IIA therapeutically reduces LPS-induced acute lung injury by inhibiting inflammation and apoptosis in mice
Aim:To study the effects of tanshinone IIA (TIIA) on lipopolysaccharide (LPS)-induced acute lung injury in mice and the… 
Highly Cited
2013
Highly Cited
2013
Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels
The protective actions of tanshinones on hypoxia-induced cell damages have been reported, although the mechanisms have not been… 
Highly Cited
2013
Highly Cited
2013
Pharmacokinetics and atherosclerotic lesions targeting effects of tanshinone IIA discoidal and spherical biomimetic high density lipoproteins.
Highly Cited
2012
Highly Cited
2012
An NQO1-Initiated and p53-Independent Apoptotic Pathway Determines the Anti-Tumor Effect of Tanshinone IIA against Non-Small Cell Lung Cancer
NQO1 is an emerging and promising therapeutic target in cancer therapy. This study was to determine whether the anti-tumor effect… 
Highly Cited
2011
Highly Cited
2011
Tanshinone IIA Inhibits miR-1 Expression through p38 MAPK Signal Pathway in Post-infarction Rat Cardiomyocytes
Tanshinone IIA is a fat-soluble pharmacologically active ingredient of Danshen, a well-known traditional Chinese medicine used… 
Highly Cited
2009
Highly Cited
2009
The role of tanshinone IIA in the treatment of obesity through peroxisome proliferator-activated receptor gamma antagonism.
Peroxisome proliferator-activated receptor (PPAR) gamma is a nuclear receptor that coordinates carbohydrate and lipid metabolism… 
Highly Cited
2009
Highly Cited
2009
Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats.
Tanshinone IIA (Tan IIA), a derivative of phenanthrenequinone isolated from Salvia miltiorrhiza, has been widely used for… 
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