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tandospirone

Known as: 3a,4,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1H-isoindole-1,3(2H)-dione, (1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-Piperazinyl)Butyl)-2,3-Norbornanedicarboximide, 4,7-Methano-1H-Isoindole-1,3(2h)-Dione, Hexahydro-2-(4-(4-(2-Pyrimidinyl)-1-Piperazinyl)Butyl)-, (3a-Alpha,4Beta,7Beta,7a-Alpha)- 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (5)

Anti-Anxiety AgentsIsoindolesPiperazinesPyrimidines

Narrower (1)

SM 3997
Tandospirone Citrate

Papers overview

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2008
2008
Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats
2008
2008
Rebound insomnia induced by abrupt withdrawal of hypnotics in sleep-disturbed rats.
2007
2007
5-HT1A receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus: Time dependence and regional differences
2005
2005
Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo
Tandospirone, an azapirone, is a selective serotonin1A (5-HT1A) receptor agonist. The effects of tandospirone on plasma hormones… 
2003
2003
Clinical efficacy of tandospirone augmentation in patients with major depressive disorder: A randomized controlled trial
Abstract The purpose of the present paper was to investigate the efficacy of augmentation of clomipramine (CMI) by tandospirone… 
2002
2002
Beneficial effects of tandospirone on ataxia of a patient with Machado‐Joseph disease
Abstract Tandospirone citrate (tandospirone) is an anti‐anxiety drug that acts by combining with serotonin receptor (5… 
2000
2000
Monoamine oxidase inhibitors reduce conditioned fear stress-induced freezing behavior in rats.
1993
1993
5-HT1A agonists disrupt memory of fear conditioning in mice
1992
1992
5-HT2/5-HT1C receptor-mediated facilitatory action on unit activity of ventral horn cells in rat spinal cord slices.
1992
1992
Kinetics, Brain Uptake, and Receptor Binding of Tandospirone and Its Metabolite l-(2‐Pyrimidinyl)-piperazine
Tandospirone is an azaspirodecanedione derivative under investigation as an antidepressant. Metabolism of tandospirone in humans… 
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