tRNA processing

Known as: tRNA maturation 
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. [GOC:jl, PMID:12533506]
National Institutes of Health

Papers overview

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2016
2016
Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR-Cas9-Mediated Genome Editing in Yarrowia lipolytica.
The oleaginous yeast Yarrowia lipolytica is a valuable microbial host for chemical production because it has a high capacity to… (More)
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Review
2011
Review
2011
Unexpected functions of tRNA and tRNA processing enzymes.
tRNA and tRNA processing enzymes impact more than protein production. Studies have uncovered roles for tRNA in the regulation of… (More)
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Highly Cited
2010
Highly Cited
2010
Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA
Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA processing. We report the crystal structure of the… (More)
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Highly Cited
2007
Highly Cited
2007
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration.
Encapsidation of host restriction factor APOBEC3G (A3G) into vif-deficient human immunodeficiency virus type 1 (HIV-1) blocks… (More)
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2005
2005
The pre-tRNA nucleotide base and 2'-hydroxyl at N(-1) contribute to fidelity in tRNA processing by RNase P.
Fidelity in tRNA processing by the RNase P RNA from Escherichia coli depends, in part, on interactions with the nucleobase and 2… (More)
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Highly Cited
2002
Highly Cited
2002
Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli.
RNase E, an essential endoribonuclease in Escherichia coli, is involved in 9S rRNA processing, the degradation of many mRNAs, and… (More)
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Highly Cited
1998
Highly Cited
1998
Nucleolar localization of early tRNA processing.
There is little information as to the location of early tRNA biosynthesis. Using fluorescent in situ hybridization in the budding… (More)
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Review
1998
Review
1998
Relics from the RNA World
An RNA world is widely accepted as a probable stage in the early evolution of life. Two implications are that proteins have… (More)
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1995
1995
The tRNA processing enzyme RNase T is essential for maturation of 5S RNA.
The maturation of 5S RNA in Escherichia coli is poorly understood. Although it is known that large precursors of 5S RNA… (More)
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1980
1980
Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs
By using conditional loss of suppression an an assay, we have been successful in screening for a yeast mutant which is defective… (More)
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