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tRNA processing

Known as: tRNA maturation 
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. [GOC:jl, PMID:12533506]
National Institutes of Health

Papers overview

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2011
2011
Maf1 Protein, Repressor of RNA Polymerase III, Indirectly Affects tRNA Processing*
Maf1 is negative regulator of RNA polymerase III in yeast. We observed high levels of both primary transcript and end-matured… Expand
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Highly Cited
2011
Highly Cited
2011
Archaeal 3′-phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation
Intron removal from tRNA precursors involves cleavage by a tRNA splicing endonuclease to yield tRNA 3′-halves beginning with a 5… Expand
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Highly Cited
2010
Highly Cited
2010
Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA
Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA processing. We report the crystal structure of the… Expand
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Highly Cited
2007
Highly Cited
2007
Human Immunodeficiency Virus Type 1 cDNAs Produced in the Presence of APOBEC3G Exhibit Defects in Plus-Strand DNA Transfer and Integration
ABSTRACT Encapsidation of host restriction factor APOBEC3G (A3G) into vif-deficient human immunodeficiency virus type 1 (HIV-1… Expand
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Highly Cited
2002
Highly Cited
2002
Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli.
RNase E, an essential endoribonuclease in Escherichia coli, is involved in 9S rRNA processing, the degradation of many mRNAs, and… Expand
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Highly Cited
2000
Highly Cited
2000
Defects in tRNA Processing and Nuclear Export InduceGCN4 Translation Independently of Phosphorylation of the α Subunit of Eukaryotic Translation Initiation Factor 2
ABSTRACT Induction of GCN4 translation in amino acid-starved cells involves the inhibition of initiator tRNAMetbinding to… Expand
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Highly Cited
1998
Highly Cited
1998
Nucleolar localization of early tRNA processing.
There is little information as to the location of early tRNA biosynthesis. Using fluorescent in situ hybridization in the budding… Expand
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Highly Cited
1995
Highly Cited
1995
The tRNA processing enzyme RNase T is essential for maturation of 5S RNA.
  • Z. Li, M. Deutscher
  • Proceedings of the National Academy of Sciences…
  • 1995
    • Corpus ID: 20138773
The maturation of 5S RNA in Escherichia coli is poorly understood. Although it is known that large precursors of 5S RNA… Expand
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Highly Cited
1987
Highly Cited
1987
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing.
Saccharomyces cerevisiae strains carrying los1-1 mutations are defective in tRNA processing; at 37 degrees C, such strains… Expand
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Highly Cited
1980
Highly Cited
1980
Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs
By using conditional loss of suppression an an assay, we have been successful in screening for a yeast mutant which is defective… Expand
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