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t(14;20)

A chromosomal translocation involving chromosome 14 and chromosome 20.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Cytogenetic abnormalities in multiple myeloma: association with disease characteristics and treatment response
Cytogenetic abnormalities are found in most multiple myeloma (MM) patients. Although their prognostic value has been well studied… 
2015
2015
Outcomes Among High-Risk and Standard-Risk Multiple Myeloma Patients Treated With High-Dose Chemotherapy and Autologous Hematopoietic Stem-Cell Transplantation.
Highly Cited
2013
Highly Cited
2013
Multiple myeloma: 2013 update on diagnosis, risk‐stratification, and management
Multiple myeloma accounts for approximately 10% of hematologic malignancies. 
Review
2013
Review
2013
Molecular pathogenesis of multiple myeloma: basic and clinical updates
Multiple myeloma is divided into two distinct genetic subtypes based on chromosome content. Hyperdiploid myeloma is characterized… 
Highly Cited
2013
Highly Cited
2013
Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.
Translocations in myeloma are thought to occur solely in mature B cells in the germinal center through class switch recombination… 
2013
2013
A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR
A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR 
Review
2012
Review
2012
Multiple myeloma: 2012 update on diagnosis, risk‐stratification, and management
Disease overview: Multiple myeloma accounts for ∼10% of all hematologic malignancies. 
Review
2010
Review
2010
ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES: A CONTINUING MEDICAL EDUCATION SERIES Multiple myeloma: 2011 update on diagnosis, risk-stratification, and management
Disease overview: Multiple myeloma is malignant plasma-cell disorder that accounts for 10% of all hematologic malignancies… 
Highly Cited
2009
Highly Cited
2009
Identification of primary MAFB target genes in multiple myeloma.
Highly Cited
2001
Highly Cited
2001
Ectopic Expression of MAFB Gene in Human Myeloma Cells Carrying (14;20)(q32;q11) Chromosomal Translocations
Chromosome 14q+, which represents a chromosomal rearrangement involving the immunoglobulin heavy chain gene (IgH) locus, is a… 
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