t(8;21)

A cytogenetic abnormality that involves a translocation between chromosomes 8 and 21.

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Topic mentions per year

1978-2018
020406019782018

Papers overview

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Highly Cited
2006
Highly Cited
2006
PURPOSE To analyze the prognostic impact of mutated KIT (mutKIT) in core-binding factor acute myeloid leukemia (AML) with inv(16… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND In patients with acute myeloid leukemia (AML) a combination of methods must be used to classify the disease, make… (More)
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Highly Cited
2001
Highly Cited
2001
The transcription factor CCAAT/enhancer binding protein α, or C/EBPα, encoded by the CEBPA gene, is crucial for the… (More)
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Highly Cited
2000
Highly Cited
2000
Leukemia-specific AML1/ETO transcripts are detectable in most patients with t(8;21) acute myelogenous leukemia (AML) in long-term… (More)
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Highly Cited
1998
Highly Cited
1998
t(8;21) is one of the most frequent translocations associated with acute myeloid leukemia. It produces a chimeric protein, acute… (More)
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Highly Cited
1998
Highly Cited
1998
The t(8;21) translocation between two genes known as AML1 and ETO is seen in approximately 12-15% of all acute myeloid leukemia… (More)
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Highly Cited
1995
Highly Cited
1995
The AML-1/CBF beta transcription factor complex is targeted by both the t(8;21) and the inv(16) chromosomal alterations, which… (More)
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Highly Cited
1993
Highly Cited
1993
The t(8;21) translocation is one of the most frequent chromosome abnormalities in acute myeloid leukemia. It has been shown that… (More)
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Highly Cited
1992
Highly Cited
1992
We have developed a restriction map of the chromosome 21 breakpoint region involved in t(8;21)(q22;q22.3) acute myelogenous… (More)
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Highly Cited
1991
Highly Cited
1991
The t(8;21)(q22;q22) translocation is a non-random chromosomal abnormality frequently found in patients with acute myeloid… (More)
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