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t(2;13)
A cytogenetic abnormality that involves a translocation between chromosomes 2 and 13.
National Institutes of Health
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Related topics
Related topics
2 relations
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 2
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas.
E. Davicioni
,
F. Finckenstein
,
V. Shahbazian
,
J. Buckley
,
T. Triche
,
M. Anderson
Cancer research
2006
Corpus ID: 14616183
Alveolar rhabdomyosarcomas (ARMS) are aggressive soft-tissue sarcomas affecting children and young adults. Most ARMS tumors…
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Review
2001
Review
2001
Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
F. Barr
Oncogene
2001
Corpus ID: 9593620
The chromosomal translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are characteristic of alveolar rhabdomyosarcoma, a pediatric…
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Highly Cited
1999
Highly Cited
1999
Negative Regulation of the Forkhead Transcription Factor FKHR by Akt*
E. Tang
,
G. Núñez
,
F. Barr
,
K. Guan
The Journal of Biological Chemistry
1999
Corpus ID: 20541878
The FKHR gene was first identified from its disruption by the t(2;13) chromosomal translocation seen in the pediatric tumor…
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Highly Cited
1998
Highly Cited
1998
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily.
M. J. Anderson
,
C. Viars
,
S. Czekay
,
W. Cavenee
,
K. Arden
Genomics
1998
Corpus ID: 31122040
Alveolar rhabdomyosarcomas are associated with unique chromosomal translocations t(2;13) and t(1;13), which arise from fusion of…
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Highly Cited
1996
Highly Cited
1996
Pax3 modulates expression of the c-Met receptor during limb muscle development.
J. Epstein
,
D. Shapiro
,
J. Cheng
,
P. Lam
,
R. Maas
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 42208700
Pax3 is a transcription factor whose expression has been used as a marker of myogenic precursor cells arising in the lateral…
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Highly Cited
1995
Highly Cited
1995
The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3.
W. Fredericks
,
N. Galili
,
+4 authors
F. Rauscher
Molecular and cellular biology
1995
Corpus ID: 21367024
Alveolar rhabdomyosarcomas are pediatric solid tumors with a hallmark cytogenetic abnormality: translocation of chromosomes 2 and…
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Highly Cited
1994
Highly Cited
1994
Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma.
R. Davis
,
C. D'Cruz
,
M. Lovell
,
J. Biegel
,
F. Barr
Cancer research
1994
Corpus ID: 431788
Although the t(2;13)(q35;q14) translocation has been found in most cases of the pediatric cancer alveolar rhabdomyosarcoma…
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Highly Cited
1993
Highly Cited
1993
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
N. Galili
,
R. J. Davis
,
+5 authors
F. Barr
Nature Genetics
1993
Corpus ID: 12374322
We have examined the structure and expression of the products associated with the t(2;13)(q35;q14) translocation associated with…
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Highly Cited
1993
Highly Cited
1993
Alveolar rhabdomyosarcoma with the t(2;13): cytogenetic findings and clinicopathologic correlations.
E. Douglass
,
D. Shapiro
,
+6 authors
D. Parham
Medical and pediatric oncology
1993
Corpus ID: 43241264
We describe here the clinical and pathologic features associated with a specific translocation, t(2;13), in alveolar…
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Highly Cited
1987
Highly Cited
1987
A specific chromosomal abnormality in rhabdomyosarcoma.
E. Douglass
,
M. Valentine
,
+5 authors
A. Green
Cytogenetics and cell genetics
1987
Corpus ID: 46798090
A specific chromosomal abnormality, t(2;13)(q35;q14), was discovered in five cases of advanced rhabdomyosarcoma. It was…
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